inducible nitric oxide synthase


Also found in: Acronyms.

inducible nitric oxide synthase

the inducible isoform of nitric oxide synthase (NOS) found within phagocytic cells (Kupffer cells, macrophages), hepatocytes, and smooth muscle cells.
See also: nitric oxide synthase, nitric oxide.
Farlex Partner Medical Dictionary © Farlex 2012
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Inducible nitric oxide synthase and vein graft performance in patients undergoing coronary artery bypass surgery: physiological or pathophysiological role?
An inhibitor of inducible nitric oxide synthase ameliorates experimental autoimmune myocarditis in Lewis rats.
Inducible nitric oxide synthase (iNOS) mRNA expression level in lung tissues of rats measured using real-time quantitative polymerase chain reaction (RT-qPCR)
Barbul, "Differential cytokine expression in skin graft healing in inducible nitric oxide synthase knockout mice," Plastic and Reconstructive Surgery, vol.
Lianos, "Effects of all-transretinoic acid (atRA) on inducible Nitric oxide synthase (iNOS) activity and transforming growth factor beta-1 production in experimental anti-GBM antibody-mediated glomerulonephritis," Inflammation, vol.
Evans, "Lipopolysaccharide Treatment in Vivo Induces Widespread Tissue Expression of Inducible Nitric Oxide Synthase mRNA," Biochemical and Biophysical Research Communications, vol.
showed that MAPC, in a cyclooxygenase 2- (COX-2-) dependent manner, suppressed the secretion of TNF-[alpha] in M1 inflammatory macrophages while, at the same time, inflammatory macrophages triggered the immunomodulatory properties of MAPC, including an increased expression of immunomodulatory mediators (inducible nitric oxide synthase (iNOS) and COX-2), chemokines, and chemokine receptors.
Chen, "Inducible nitric oxide synthase mediates cytokine release: the time course in conscious and septic rats," Life Sciences, vol.
X-ray radiation-induced oxidative stress is associated with elevated nitric oxide concentration and inducible nitric oxide synthase expression in H9c2 cells
NF-[kappa]B, which has moved to the nucleus, induces the gene expression of inflammatory cytokine, inducible nitric oxide synthase (iNOS), and cyclooxygenase-2 (COX-2), while NO, the indicator of an inflammation is synthesized by NO synthase (NOS) from L-arginine (Shon et al., 2012).
Primary and secondary antibodies against inducible nitric oxide synthase (iNOS), cyclooxygenase 2 (COX2), extracellular signal regulated kinase (ERK), janus kinase (JNK), p38, Bax, Bcl-2, cleaved caspase-3, nuclear factor erythroid 2-related factor 2 (Nrf2), and tubulin, were purchased from Cell Signaling (Beverly, MA, USA).
Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase. Cell 1995;81:641-50.