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In human genetics, the patient or member of the family that brings a family under study.
Synonym(s): index case
[L. probo, to test, prove]
Farlex Partner Medical Dictionary © Farlex 2012
1. The earliest identified occurrence of a disease or disorder, usually as part of an epidemiological investigation of a patient population or a genetic study of a family.
2. The first patient who has such a disease or disorder. Also called proband, propositus.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.
index caseSee Index patient, see there.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
in·dex case(in'deks kās)
The first case in the investigation of the outbreak of a potentially epidemic disease.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
The first case of a contagious disease in a group or population that serves to call attention to the presence of the disease.
Mentioned in: Syphilis
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.