inclusion body myositis


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inclusion body myositis

a slowly progressive inflammatory myopathy with a male predominance and preferential weakness onset in the quadriceps muscles, finger flexors, or pharyngeal muscles. Inflammatory infiltrate can be observed, with a predominance of CD8+ T cells.

inclusion body myositis

a progressive inflammatory myopathy primarily involving muscles of the pelvic region and legs, usually seen in older people. The muscles are infiltrated by mononuclear inflammatory cells, sarcoplasmic vacuoles, masses of filaments and filamentous microtubules, and sometimes eosinophilic bodies.

inclusion body myositis

A type of idiopathic myositis that is not autoimmune and does not respond to immunosuppressive therapy, a clinical diagnosis of exclusion, confirmed by typical histologic features Clinical Slowly progressive disease of middle-aged ♂, beginning in legs, causing atrophy and weakness of quadriceps, sparing facial and oropharyngeal muscles EMG Abnormal electrical 'irritation', slowing of nerve conduction and ↑ wave amplitude
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Common variable immunodeficiency (CVID) and inclusion body myositis (IBM).
Ubiquitin immunostaining and inclusion body myositis: study of 30 patients with inclusion body myositis.
The program is currently in a Phase I/II trial at Nationwide Children's Hospital in adult patients with Becker muscular dystrophy and inclusion body myositis, a trial funded by the foundation Parent Project Muscular Dystrophy.
The Phase I/II trial, funded by a grant from Parent Project Muscular Dystrophy, is enrolling patients with Becker muscular dystrophy and inclusion body myositis.