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Related to inclusion body: inclusion body disease
An abnormal structure in a cell nucleus or cytoplasm having characteristic staining properties and usually composed of protein, occurring primarily in infectious diseases, especially viral infections such as rabies.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.
inclusion bodyA generic term for a circumscribed mass of intracellular or intranuclear material, which is often “foreign” to the cell or nucleus.
Metal (e.g., lead, mercury); viral particles (e.g., herpes, CMV); metabolically inactive materials (e.g., ceroid, Mallory bodies).
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
- a body present in the nuclei or cytoplasm of cells infected by viruses or other intracellular parasites.
- an insoluble protein aggregate that may form a crystalline structure inside host cells. An inclusion body may form as a result of overproduction of recombinant or normal protein in an overexpression system (see GENE EXPRESSION).
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005