inborn lysosomal disease

in·born ly·so·so·mal dis·ease

inherited disorder of one or more degradative enzymes normally located in lysosomes leading to accumulation (storage) of abnormal quantities of a substance, such as a glycosaminoglycan as in Hurler syndrome or a lipopolysaccharide as in Gaucher disease.

inborn lysosomal disease

one of many inherited disorders of metabolism involving degradative enzymes normally located in lysosomes. The condition leads to storage of abnormal amounts of lysosomal agents. Also called lysosomal storage disease.