inactivation


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Related to inactivation: Insertional inactivation

inactivation

 [in-ak″tĭ-va´shun]
the destruction of activity, as of a virus, by the action of heat or another agent.

in·ac·ti·va·tion

(in'ak-ti-vā'shŭn),
The process of destroying or removing the activity or the effects of an agent or substance; for example, the complementary effect of a serum may be destroyed by means of inactivation at 56°C for 30 minutes.
References in periodicals archive ?
If this inactivation does not occur efficiently, the neural tube will not form properly.
Virus-specific thermostability and heat inactivation profiles of alphaviruses.
For the lowest [[sigma].sub.N] (Figure 1(a)), the inactivation does not exceed 2% and, in some cases, assumes negative values, indicating an increase of the mean firing frequency instead of a reduction.
Belmont, "Methylation of HpaII and HhaI sites near the polymorphic CAG repeat in the human androgen-receptor gene correlates with X chromosome inactivation," American Journal of Human Genetics, vol.
The inactivation process of microorganisms in tempeh increased in relation to the increase of incubation period of pressurized C[O.sub.2] (see Table 1).
This indicates inactivation of enzyme at 37[degrees]C on increasing incubation period.
Steady-state inactivation was shifted by -9.2 [+ or -] 0.8 mV, and recovery time from inactivation also increased (recovery time constant in control: 1.51 [+ or -] 0.06 ms, n =12; hypoxia: 2.21 [+ or -]0.12ms, n =12; p <0.05).
MscS exhibits prominent voltage-dependent inactivation under depolarizing conditions [13, 19-21].
The primary purpose of the strategy used by 4/1 IBCT was to gain effective use of personnel in order to maintain multiple units and centralized control of the logistics involved with the inactivation. The 4/1 IBCT commander designated equipment divestiture as the decisive operation for inactivation and named the 701st Brigade Support Battalion (BSB) as the main effort for the brigade.
Microbial inactivation was detected using the spread plate method.
Viral inactivation is carried out at all levels of pharmaceutical and biopharmaceutical manufacturing process to minimize the risk of product contamination.
In isothermally-processed foodstuff, enzymatic inactivation are modeled using first-order kinetic model frequently expressed by k and D values, as k represents the inactivation rate constant ([min.sup.-1]) and D is the time period (min) necessary for the enzyme to lose 90% of its activity (TEREFE et al 2009).