in-transit metastasis

in-transit metastasis

in melanoma, a metastatic deposit occurring in the lymphatic pathway between the primary tumor and its draining lymph nodes.
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pN2c: Satellite or in-transit metastasis without nodal metastasis
pN3: Metastasis in 4 or more regional lymph nodes or matted metastatic nodes or in-transit metastasis or satellites(s) with metastasis in regional node(s)
In-transit metastasis is defined as intralymphatic tumor in skin or subcutaneous tissue more than 2 cm from the primary tumor but not beyond the nearest regional lymph node basin.