in-stent restenosis

in-stent restenosis

Interventional cardiology Scar-induced reclosure of a previously stenosed coronary artery, a complication seen in ±20% of Pts undergoing stent placement for CAD. See Coronary artery disease, Stent. Cf Late stent thrombosis.
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Dual therapy stent is advantageous as compared to drug-eluting stents and bare metal stents as they offer lower rates of in-stent restenosis, and requires subsequent medical interventions.
The all-metal stents also were associated with higher rates of in-stent restenosis and sub-acute stent thrombosis, the latter of which is a potentially fatal complication occurring up to 30 days after implantation.
During this admission, the patient underwent nonselective coronary angiography due to the previous excessively protruding stent and showed in-stent restenosis (ISR) at ostial LMCA [Figure 1]d.
The freedom from clinically-driven target lesion revascularization rate calculated using Kaplan Meier survival estimates was 76.9% in a real-world patient cohort with a mean lesion length of 12.09 +/- 9.54 cm, 18.0% in-stent restenosis, 35.5% occluded lesions, and 39.9% diabetic subjects.
Her past medical history included coronary artery bypass graft (CABG) 20 years ago and subsequent multiple prior percutaneous coronary interventions (PCIs) to her right coronary artery (RCA) and left circumflex artery (LCx), and most recently 10 months before with a 2.75 x 14 mm Resolute Integrity drug-eluting stent (DES) for an in-stent restenosis of her mid-RCA.
For this purpose, we retrospectively reviewed the medical records of patients treated for carotid stenosis in a single institution in Southwest China and analyzed stroke recurrence, incidence of all-cause death, disability, and rate of in-stent restenosis later than 120 days after CAS.
It revealed a mid-LAD stent fracture with 70% in-stent restenosis (fractional flow reserve of 0.78) (Figure 4).
Although there have been advances in the peripheral stent technology in recent times, the most important issue of the stenting is still in-stent restenosis in long-term follow-up, and its treatment is difficult [3].
However, sometimes scar tissue forms inside the stent and impairs blood flow; this is called "in-stent restenosis." Also, although it is rare, blood clots may form inside of stents; to prevent this, it is critical that you take anti-clotting medications exactly as your doctor has prescribed them.
The product is indicated for a variety of uses, including: balloon dilatation of the stenotic portion of a coronary artery or bypass graft stenosis in patients evidencing coronary ischemia for the purpose of improving myocardial perfusion; balloon dilatation of a coronary artery occlusion for the treatment of acute myocardial infarction; and dilatation of in-stent restenosis and post-delivery expansion of balloon expandable coronary stents.
Both products are indicated for balloon dilatation of the stenotic portion of a coronary artery or bypass graft stenosis in patients evidencing coronary ischemia for the purpose of improving myocardial perfusion, balloon dilatation of a coronary artery occlusion for the treatment of acute myocardial infarction as well as for dilatation of in-stent restenosis and post-delivery expansion of balloon expandable coronary stents.

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