Outcome is not predicted by lymphovascular invasion, ulceration or nodal status or related to the presence of melanin or in situ melanoma
Only advanced age was predictive of severe histologic dysplasia or in situ melanoma
In 2004, there were 55,000 new cases of invasive melanoma in the United States and 41,000 cases of in situ melanoma
. "Therefore, there are about 100,000 cases which require a procedure every year," Dr.
If the incidence of in situ melanoma
is added in, the lifetime risk for any form of melanoma in 2003 is 1 case in every 39 people.
In a separate study, Ferris et al (37) evaluated dermatologist biopsy sensitivity and specificity with and without the Pigmented Lesion Assay data in a Web-based multiple-reader, multiple-case study wherein 45 board-certified dermatologists evaluated the clinical and dermatoscopic images of 8 invasive or in situ melanomas
and 52 nonmelanomas (including 42 atypical nevi and 2 conventional nevi, as well as 8 lentigines or keratosis).