Conjunctiva impression cytology is one of the most practical, fast, safe and economical method to examine the changes of conjunctiva cells.
This study was planned to examine the changes in the upper tarsal conjunctiva in new continuous gas-permeable contact lens (CWRGP) wearers using impression cytology procedure.
To the best of our knowledge, there is no reported data available on subjects wearing CWRGP using impression cytology methods.
However, samples of conjunctiva cells were collected only at baseline and after 3 months of wearing the lenses using impression cytology.
Impression cytology has been used widely to evaluate several ocular surface disorders, monitoring the effect of treatment such as contact lens wear and documenting sequential changes in the conjunctival and corneal surface over time (1, 11-13).
4% of the asymptomatic soft contact lens wearing eyes showed abnormal conjunctiva impression cytology changes within the same period (6).
Interestingly, in recent times, impression cytology has proved to be very effective in the diagnosis of ocular surface diseases, better understanding of the pathophysiology of the diseases related to ocular surface and provides biomarkers which could be used as outcome measures (7).
This study concludes that well adapted and asymptomatic continuous RGP wearers for 3 months show no adverse effects to their conjunctival epithelia as measured by impression cytology.
Conjunctival impression cytology in dry eye states.