importin


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importin

a protein involved in transporting molecules into the NUCLEUS.

importin

a protein that binds to a 'cargo' protein in the cytoplasm and transports the cargo through the nuclear pore complex into the nucleus. See also exportin.
References in periodicals archive ?
It is also possible that FA forms adducts with amino acid residues of histone chaperones, such as CAF-1, HIRA and ASF1, as well as with histone translocator proteins, such as Importin 4.
Coat proteins of Rice tungro bacilliform virus and Mungbean yellow mosaic virus contain multiple nuclear-localization signals and interact with importin a.
The nuclear translocation of GH is mediated by GHR, and the nuclear translocation of the GH-GHR complex is mediated by the importin a/p system (Conway-Campbell et al.
2) Proline-tyrosine-NLS (PY-NLS), characterized by a pro-line-tyrosine AA domain in the N-terminal, which allows the protein to bind to importin [beta]2 (also known as transportin or karyopherin [beta]2), and then relocates the cargo protein into the nucleus (15).
287-289) Proteomic analysis has also shown association of NPMALK with molecules involved in DNA repair (Ku86, Ku70, PARP1 [poly(ADP-ribose) polymerase 1], MSH2, PCNA [proliferating cell nuclear antigen], and MCM6 [mini-chromosome maintenance deficient 6 homolog]) (283) and has revealed other new binding partners for NPM-ALK, including Nup98 and importin 8 (subcellular protein transport), Stim 1 (calcium signaling), and 82FIP (RNA regulation).
On this question that Pakistan is an agricultural country and has one of the best irrigation systems then why it was importin food items from abroad.
Most amino acid differences occurred in the NS5 protein, which is associated with cytoplasmic RNA replication because it contains an RNA-dependent RNA polymerase, S-adenosylmethionine methyltransferase, and importin [beta]-binding motifs (28).
Similarly, in hippocampal neurons, NMDA activation or LTP induction, but not depolarization, leads to translocation of importin (Thompson et al, 2004).
Rather than address fundamental problems by investing in youth development, Scottish football has been importin mediocrity because in many cases the foreign player is cheaper.
I would blame the Dutch for importin g disease-carrying plants.
We also note a concurrent increase in the expression of components of the ubiquitin-proteasome proteolytic pathway (PAD1, SUG1; Figure 5F) and genes whose products are required for the nuclear import and export of proteins (IMPORTIN [alpha] 2, IMPORTIN [alpha] 3, RAE1, G3BP2; Figure 5C), indicating that [E.