impaired glucose tolerance


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Related to impaired glucose tolerance: Impaired fasting glucose

im·pair·ed glu·cose tol·er·ance

excessive levels (110-126 mg/dL) of blood glucose developing after a carbohydrate-rich meal or test dosage of glucose (usually 75 g). Not necessarily diagnostic for diabetes mellitus.

impaired glucose tolerance (IGT)

[imperd′]
Etymology: L, impejorare, to make worse; Gk, glykys, sweet; L, tolerare, to endure
a condition in which fasting plasma glucose levels are higher than normal but lower than those diagnostic of diabetes mellitus. In some patients this represents a stage in the natural history of diabetes, but in some people IGT either does not progress or ends, and glucose tolerance reverts to normal. Also called impaired prediabetes. See also diabetes mellitus.

im·pair·ed glu·cose tol·er·ance

(IGT) (im-pārd glūkōs tolĕr-ăns)
A disordered state in which a patient does not process glucose properly but such activity does not confirm a diagnosis of diabetes mellitus.
See also: Type 1 diabetes, Type 2 diabetes

impaired glucose tolerance

Abbreviation: IGT
Altered glucose metabolism in which fasting blood sugars are less than 126 mg/dl, and blood sugar levels are over 140 mg/dl but less than 200 mg/dl 2 hr after drinking 75 g of glucose.

CAUTION!

Having either impaired glucose tolerance or impaired fasting glucose predisposes patients to diabetes mellitus, heart attack, stroke, and early death. Patients with abnormal glucose metabolism ought to receive professional dietary counseling. They should also begin a program of regular physical exercise.
See also: tolerance
References in periodicals archive ?
In patients with a 5-year CVD risk of 5%-10%, the cost-effectiveness of statins varied based on baseline diabetes risk: $8,900-$16,400/QALY for normal glucose tolerance, $16,300-$73,300/QALY for impaired glucose tolerance, and $326,700/QALY for IGT and impaired fasting glucose.
At 3 months post partum, glycemic parameters progressively increased from normal glucose challenge test with normal glucose tolerance to abnormal glucose challenge test with normal glucose tolerance to 2- or 3-hour gestational impaired glucose tolerance to 1 -hour GIGT to gestational diabetes mellitus.
The Indian Diabetes Prevention Programme shows that lifestyle modification and metformin prevent type 2 diabetes in Asian Indian subjects with impaired glucose tolerance (IDPP-1).
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Impaired glucose tolerance was diagnosed when the fasting plasma glucose concentration was <1260 mg/L and the 120-min plasma glucose concentration during the oral glucose tolerance test was greater than 1400 mg/L but less than 2000 mg/L (19).
Each pregnancy increased a woman's chance of develping impaired glucose tolerance by 10 percent, they found.
A high-fat meal in people with diabetes and impaired glucose tolerance appears to trigger the passage of bacterial endotoxins through the intestinal wall, adding to the load of inflammatory cytokines that have already been implicated in the disease, Alison Harte, Ph.
The branched-chain amino acids may also help reduce impaired glucose tolerance, which contributes to obesity.
An abstract entitled No Generation of Insulin Antibodies in Subjects with Impaired Glucose Tolerance Treated With Buccal Spray Insulin is a poster presentation at the symposium.
SAN FRANCISCO--People with impaired glucose tolerance were 81% less likely to develop type 2 diabetes over a 3-year period if treated with pioglitazone, according to a prospective, randomized, double-blind, placebo-controlled study of 602 patients.
Growing evidence suggests that patients with diabetes mellitus or impaired glucose tolerance have an increased risk of developing cancer, he noted.