immunosuppressive


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immunosuppressive

 [im″u-no-sŭ-pres´iv]
1. pertaining to or inducing immunosuppression.

im·mu·no·sup·pres·sive

(im'yū-nō-sū-pres'iv),
1. Denoting or inducing immunosuppression.
2. Synonym(s): immunosuppressant

immunosuppressive

[-səpres′iv]
1 adj, pertaining to a substance or procedure that lessens or prevents an immune response.
2 n, an immunosuppressive agent. The immunosuppressive drugs used most frequently to prevent allograft rejection are the interleukin 2 production inhibitors cycloSPORINE and tacrolimus, the cytotoxic purine antimetabolite azathioprine, the alkylating agent cyclophosphamide, and the adrenocorticosteroid predniSONE. Methotrexate, cytarabine, dactinomycin, and thioguanine are also potent immunosuppressive drugs. Monoclonal antibodies against the T cell receptor (muromonab-CD3) and interleukin 2 receptors (basiliximab and daclizumab) are also administered for immunosuppression. The use of some of these agents is being explored for the treatment of autoimmune diseases such as rheumatoid arthritis and systemic lupus erythematosus.

Immunosuppressive

Any agent that suppresses the immune response of an individual.

immunosuppressive

1. pertaining to or inducing immunosuppression.
2. an agent that induces immunosuppression.
References in periodicals archive ?
The EP4 receptor is strongly associated with an immunosuppressive and tumor promotive effect via immune cell modulation.
In immunocompromised patients, such as those with acquired immunodeficiency syndrome (AIDS), those receiving immunosuppressive therapy and those who have undergone organ transplantation, CMV exposure can lead to a life-threatening opportunistic infection.
The more important question nowadays concerns the treatment requirements of AIH patients with cirrhosis who do not have indications for immunosuppressive treatment.
CMS correctly determined that immunosuppressive drugs meet the first of the two standards proposed for inclusion in the protected class, and our organizations concur.
This study provides provocative preliminary data on possible immunosuppressive regimes for die transplantation of non-self stem cells into patients with spinal cord disorders, such as ALS" said Dr.
These vaccinations can be considered in patients who are on high-dose immunosuppressive drugs or biologic agents before therapy.
Whether or not this same signature will identify those kidney transplant recipients still taking immunosuppressive medications who are predisposed to developing tolerance in the future remains unknown," said Newell.
Calabrese wrote: "An indirect immunosuppressive effect on the host immune response can be responsible for the enhanced HBV viremia.
With increasing immunocompromised hosts resulting from immunosuppressive therapy and HIV infections, as well as improved diagnostic tests, histoplasmosis might be an emergent infectious disease in Taiwan in the future.
Temporary discontinuation of immunosuppressive treatment and renal graft rejection.
This Notice of Allowance allows us to build our immunosuppressive patent portfolio to include TAFA93," said Dr.
Transplantation has proven to be a lucrative business for the manufacturers of immunosuppressive medications.