Because all germ cells in the perinatal rat testis immunostain
intensely for VASA in the cytoplasm, we were able to use VASA immunohistochemistry to develop an objective method for measuring germ cell aggregation, based on average germ cell cluster size, in testes from control and DBP-exposed rats at E17.
As the morphological features may be subtle and variable, HHV8-LANA1 immunostain
serves as a sensitive marker.
Two cases (11%) were submitted with negative immunostain
results for p53 from the original institution.
The integration provides a mapping between the lab's existing antibody test directory and ImmunoQuery's extensive antibody menu, enabling pathologists to tailor immunostain
orders to include antibodies available in-house whenever possible.
To confirm the diagnosis, a p16 immunostain
may be helpful to rule out HPV.
5,13) The pathologist should be aware that E-cadherin immunostain
can show cytoplasmic granular staining, which can be a source of misinterpretation and a potential diagnostic pitfall.
A and B, Photomicrographs showing focal faint cytoplasmic positivity for M30/fragmented cytokeratin 18 immunostain
in both crypts and villi of duodenal biopsy specimens from controls.
d, CD68 immunostain
highlighting histiocytes within the splenic cord and scattered sinusoidal macrophages (immunoperoxidase, original magnifications x4 [a and b] and x10 [c and d]).
a leader in reference materials for radiology and pathology, today announced the development of an integration between PowerPath(R), Impac's AP laboratory information system, and PathIQ(R), Amirsys' PathIQ ImmunoQuery immunostain
decision support system.
In one of our prior studies, we found that the combination of both basal markers as a single "cocktail" immunostain
is optimal as it enhances sensitivity and limits variability compared with either antibody used separately.
is of particular interest in inadequate biopsies because submucosa is not necessary for reliable interpretation.
The TissueInformatics TissueAnalytics(TM) software automatically determines immunostain
area and intensity, enables fixed reference comparisons, and quantifies identified structural elements within tissue -- including cells, vasculature, and matrix organization -- by a range of feature metrics, such as type, shape, size and distribution.