immunoscintigraphy

immunoscintigraphy

 [im″u-no-sin-tig´rah-fe]
scintigraphic imaging of a lesion using radiolabeled monoclonal antibodies or antibody fragments specific for antigen that is associated with the lesion.

immunoscintigraphy

/im·mu·no·scin·tig·raphy/ (-sin-tig´rah-fe) scintigraphic imaging of a lesion using radiolabeled monoclonal antibodies or antibody fragments specific for antigen associated with the lesion.

immunoscintigraphy

Imaging A procedure in which radioactively-labeled substances are administered and images obtained from body sites where the antibody localizes; the scintigraphic imaging of a CA after administrating a γ-emitting monoclonal antibody directed against a particular tumor-specific antigen

immunoscintigraphy

(im?u-no-sin-tig'ra-fe)
The imaging of specific tissues by means of their binding to radioactively labeled monoclonal antibodies; used to detect metastatic cancer. The release of radiation from the antibodies is detected and quantified.
Synonym: radioimmunoimaging
References in periodicals archive ?
The abstracts John Theurer Cancer Center will present focus on the following topics: laparoscopic adrenalectomy (horseshoe kidney), hypogonadal patients receiving clomiphene citrate or anastrozole for infertility, robot-assisted radical prostatectomy and CT-fused indium-111 capromab pendetide immunoscintigraphy in management of recurrent prostate cancer.
Immunoscintigraphy of Pneumocystis carinii pneumonia in AIDS patients.
Clinical utility of external immunoscintigraphy with the IMMU-4 technetium-99m Fab' antibody fragment in patients undergoing surgery for carcinoma of the colon and rectum: Results of a pivotal, phase III trial.
A review with experiences of aspecific bowel activity using immunoscintigraphy with 99mTc anti-granulocyte antibodies.
These other presentations are entitled, "In-111 ProstaScint imaging in prostate cancer," "Evaluation of false positives during In-111 ProstaScint immunoscintigraphy," "ProstaScint imaging in metastatic evaluation of patients cancer and assessment of post-prostatectomy recurrence," and "Combined CT/SPECT with dual-energy attenuation correction for quantitative ProstaScint imaging.
In the diagnostic field, the Company is continuing its R&D activities on molecular oncology and immunoscintigraphy tests.
Human anti-mouse antibodies are sometimes observed in patients who have been submitted to immunoscintigraphy for the detection of recurrences.
The conclusion of the study was that immunoscintigraphy with DiaCIM is useful for the diagnosis and follow-up of patients with cancers of epithelial origin.
The humanized antibody, hR3, has been shown to have the same binding affinity as the murine version, mR3, and a similar pattern of positive results would be expected using this antibody for immunoscintigraphy.
For example, in one study (85), an IgG HAMA was still detectable after 10 months, and in another study (86), it was detectable up to ~30 months after immunoscintigraphy.
He is the author of numerous scientific papers in the fields of immunology and immunoscintigraphy, and the primary inventor on seven United States Patents.
He presently serves on the Scientific Advisory Boards of both the Cancer Institute of New Jersey and Rider College, as well as the Advisory Council of the Princeton Chamber of Commerce, and is the author of numerous scientific papers in the fields of immunology and immunoscintigraphy.