immunoscintigraphy

immunoscintigraphy

 [im″u-no-sin-tig´rah-fe]
scintigraphic imaging of a lesion using radiolabeled monoclonal antibodies or antibody fragments specific for antigen that is associated with the lesion.

immunoscintigraphy

/im·mu·no·scin·tig·raphy/ (-sin-tig´rah-fe) scintigraphic imaging of a lesion using radiolabeled monoclonal antibodies or antibody fragments specific for antigen associated with the lesion.

immunoscintigraphy

Imaging A procedure in which radioactively-labeled substances are administered and images obtained from body sites where the antibody localizes; the scintigraphic imaging of a CA after administrating a γ-emitting monoclonal antibody directed against a particular tumor-specific antigen

immunoscintigraphy

(im?u-no-sin-tig'ra-fe)
The imaging of specific tissues by means of their binding to radioactively labeled monoclonal antibodies; used to detect metastatic cancer. The release of radiation from the antibodies is detected and quantified.
Synonym: radioimmunoimaging
References in periodicals archive ?
Immunoscintigraphy with three step monoclonal pretargeting technique in diagnosis of uveal melanoma: preliminary results.
Immunoscintigraphy of Pneumocystis carinii pneumonia in AIDS patients.
Clinical utility of external immunoscintigraphy with the IMMU-4 technetium-99m Fab' antibody fragment in patients undergoing surgery for carcinoma of the colon and rectum: Results of a pivotal, phase III trial.
Pretargeted immunoscintigraphy of murine tumors with indium-111-labeled bifunctional haptens.
Despite its suspected potential, the exact role of immunoscintigraphy in breast cancer detection remains to be determined.
While immunoscintigraphy can be useful in the evaluation of suspicious mammographic findings, it also may be useful in the detection of metastatic breast cancer.
As Taillefer[55] describes it, numerous studies[84-93] have evaluated a variety of imaging techniques for their potential in the evaluation of possible metastatic involvement of the axillary lymph nodes, such as axillary lymphoscintigraphy, immunoscintigraphy, fluorine-18-fluorodeoxy glucose (FDG) PET and SPECT imaging and sentinel node detection using an intraoperative gamma probe.
A review with experiences of aspecific bowel activity using immunoscintigraphy with 99mTc anti-granulocyte antibodies.
In the diagnostic field, the Company is continuing its R&D activities on molecular oncology and immunoscintigraphy tests.
Human anti-mouse antibodies are sometimes observed in patients who have been submitted to immunoscintigraphy for the detection of recurrences.
For example, in one study (85), an IgG HAMA was still detectable after 10 months, and in another study (86), it was detectable up to ~30 months after immunoscintigraphy.
Immunoscintigraphy of inflammatory processes with a technetium-99 m-labeled monoclonal antigranulocyte antibody (MAb BW 250/183).