Pigmented nails and Strongyloides stercoralis infestation causing clinical worsening in a patient treated for immunoproliferative
small intestinal disease: two unusual observations.
[alpha]-HCD, also called immunoproliferative
small intestinal disease, is associated classically with severe gastrointestinal symptoms, including abdominal pain and severe malabsorption manifested by chronic diarrhea and weight loss; it classically occurs in young adults (ages 20s to 30s) living in the Mediterranean region or Middle East, with a slight male dominance (5).
Patients with known inflammatory disease, estimated glomerular filtration rate (eGFR) < 60 mL/min/1.73[m.sup.2], serious valvular heart disease, heart failure, serious hepatic failure, acute or chronic infection, fever, muscle aches, headaches, immunoproliferative
disease, rheumatic disease, malignancy, and osteoporosis; those under 18 years of age and above 70 years of age; and those receiving antibiotics therapy were also excluded from the study .
Age-related changes in intracellular TH1/TH2 cytokine production, immunoproliferative
T lymphocyte response and natural killer cell activity in newborns, children, and adults.
Primary small intestinal lymphoma maybe broadly categorized into three groups including immunoproliferative
small intestinal disease (IPSID) lymphoma, enteropathy-associated T-cell lymphoma (EATL) and other western-type non-IPSID lymphomas.
Avanzini et al., "Age-related changes in intracellular Th1/Th2 cytokine production, immunoproliferative
T lymphocyte response and natural killer cell activity in newborns, children and adults," Biology of the Neonate, vol.
Small-bowel lymphomas are more often found in patients with celiac disease, Crohn's disease, AIDS, EBV infection, immunoproliferative
disease (IPSID), long term immunosuppressive therapy (posttransplantation) and after radiation, and/or chemotherapy [5, 21].
Those findings prompted immunostains for IgA, IgG, and IgM heavy chains, which revealed overwhelming IgA expression on the plasma cells without light chain expression, resulting in the diagnosis of immunoproliferative
small intestinal disease (IPSID).
lesions: A clinicopathologic spectrum of post-thymic T-cell proliferations.
Extramedullary plasmacytomas are immunoproliferative
monoclonal B-cell malignancies.
lesion/T-cell non-Hodgkin's lymphoma and the acquired immune deficiency syndrome: a case report and review of the literature.
Lymphomas are associated with Celiac disease, immunoproliferative
small intestinal disease (IPSID) and very rarely to Crohn's disease.