"The primary consideration will be determining whether immunological tolerance
can be temporarily relaxed without leading to detrimental autoimmune manifestations and as a means to possibly elicit HIV-1 bnAbs with vaccination," he concluded.
This suggests that B7-H1 is important to maternal immunological tolerance
of the fetal placenta.
If vertical transmission does occur, then the establishment of immunological tolerance
to ABV must be considered.
In other cases, the tumoral progression coincides with the induction of specific immunological tolerance
even during early stages of carcinogenesis.
Cholera toxin B subunit : an efficient transmucosal carrier-delivery system for induction of peripheral immunological tolerance
. Proc Natl Acad Sci USA 1994; 91 : 10795-9.
380: Immunological Tolerance
: Methods and Protocols
The drug's proposed mechanism of action is the induction or restoration of immunological tolerance
with respect to ongoing immune attack as a result of high doses of peptide periodically delivered intravenously.
(innate or acquired) is briefly introduced as "the process by which the immune system does not attack an antigen." In two expert commentaries and eight contributed chapters, international scientists examine how advances in understanding regulatory T-cells and the use of transgenic plants and other recombinant technology methods are treating such challenges as inducing immune tolerance in patients with hemophilia, kidney transplants, and thymus gland defect-related intolerance problems in Type I diabetes.
AIRE is also expressed in peripheral dendritic cells and is thought to be involved in the maintenance of peripheral immunological tolerance
. (4) Recently, (5) it has been shown that AIRE-deficient patients show reduced regulatory T-cell (TREG) activity.
Among those institutions is the JDRF/Beverly Berry Center for Immunological Tolerance
at Harvard Medical School, named for the spouse of Fresh Market owner's Ray Berry.