immunologic tolerance

tolerance

 [tol´er-ans]

1. the ability to bear something potentially difficult.

2. the ability to endure unusually large doses of a poison or toxin.

3. drug tolerance. adj., adj tol´erant.

acquired drug tolerance drug tolerance.

ambiguity tolerance the ability to withstand conflicting or complex situations without undue psychological stress.

drug tolerance a decreasing response to repeated constant doses of a drug or the need for increasing doses to maintain a constant response. See also drug dependence and habituation.

immunologic tolerance specific nonreactivity of lymphoid tissues to a particular antigen capable under other conditions of inducing immunity.

standing tolerance the amount of time an individual is capable of maintaining an erect, upright position.

tolerance test

1. an exercise test to determine the efficiency of the circulation.

2. a test to determine the body's ability to metabolize a substance or to endure administration of a drug.

im·mu·no·log·ic tol·er·ance

lack of immune response to antigen. Theories of tolerance induction include clonal deletion and clonal anergy. In clonal deletion, the actual clone of cells is eliminated whereas in clonal anergy the cells are present but nonfunctional.

Synonym(s): immunotolerance, nonresponder tolerance

immunologic, immunological

emanating from or pertaining to immunology.

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immunologic competence

see immunocompetence.

immunologic domains

in cell receptor biology, the structure of receptors is conveniently considered in terms of three functional domains: transmembrane, ligand binding and immunological; the latter contain primary antigenic regions.

immunologic fertility control

antihormone immunization.

immunologic incompetence

immunoincompetence.

immunologic injury

see immunopathy.

immunologic reactions

see immune response, immunity.

immunologic status

a reference to immunocompetence of a host.

immunologic tolerance

see immunological tolerance.