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Related to immunoglobulins: immunoglobulin G


ANTIBODIES, protective proteins produced by cloned B lymphocyte-derived plasma cells. There are five classes of immunoglobulins, the most prevalent being immunoglobulin G (IgG), or gammaglobulin which provides the body's main defence against bacteria, viruses and toxins. Immunoglobulins are Y-shaped protein molecules consisting of two inner heavy POLYPEPTIDE chains, forming a Y, and, attached to the outer side of the short arms of the Y, two light polypeptide chains. The heavy chains are held together and the light chains held to the arms, by disulphide bonds. The short arms of the Y, with the light chains, are called the Fab (fragment antigen binding) section of the antibody. The antigen combining site lies between the open ends of the light and heavy chains. See also IgA, IgD, IgE, IgG and IgM. Some immunoglobulins are prepared as drugs for the management of RHESUS incompatibility and antibody deficiency; for the prophylaxis of MEASLES and hepatitis A; to minimize fetal damage when a pregnant woman is exposed to RUBELLA; and to assist in the treatment of TETANUS and RABIES. They are marketed under such brand names as Flebogamma, Gammabulin, Gammagard, Octagam, Rhophylac, Sandoglobulin, Vigam liquid and Winrho SDF.


Any of several types of globulin proteins that function as antibodies.
References in periodicals archive ?
59% for Holstein) cows, although the concentrations of 3 major immunoglobulins, IgG, IgM, and IgA, decreased with each successive postpartum milking.
By omitting the reducing step after capturing immunoglobulins with antisera to [kappa] and [lambda] light chains, they have essentially developed an MS version of the serum free light chain immunoassay, made specific for monoclonal free light chain by visual inspection of the mass spectra (9).
Technavio's report, Global Immunoglobulin Products Market 2016-2020, has been prepared based on an in-depth market analysis with inputs from industry experts.
Objective: To determine and compare the serum levels of immunoglobulins (IgG, IgM, IgA) and CRP in autistic children and healthy controls.
Since intravenous immunoglobulins include antibodies against Th1 cytokines, they help in elimination of this imbalance.
The study evaluated the up-regulation of immunoglobulins in patients suffering from chronic rhinosinusitis to elucidate the potential activity of these antibodies.
When ghrelin was administered in combination with immunoglobulins extracted from the blood of obese patients, or with immunoglobulins derived from genetically-obese mice, they stimulated food intake more strongly.
Immunoglobulin is a glycoprotein found in blood and other body fluids that contains antibodies to protect the body against pathogens.
Amoros conducted a similar study, in 2004, on 89 healthy children in which the impact of the tonsillar surgery on the serum immunoglobulins was analyzed14.
The clinical course and the degree or type of serum immunoglobulins deficiency varies from patient to patient, hence, the word "variable".
As well as receiving horse antibodies, known as immunoglobulins, last April and the rabbit blood products over the next few months, Cara must also undergo at least one blood transfusion every fortnight as well as platelet replacements once a week.

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