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Related to immunoglobulins: immunoglobulin G


ANTIBODIES, protective proteins produced by cloned B lymphocyte-derived plasma cells. There are five classes of immunoglobulins, the most prevalent being immunoglobulin G (IgG), or gammaglobulin which provides the body's main defence against bacteria, viruses and toxins. Immunoglobulins are Y-shaped protein molecules consisting of two inner heavy POLYPEPTIDE chains, forming a Y, and, attached to the outer side of the short arms of the Y, two light polypeptide chains. The heavy chains are held together and the light chains held to the arms, by disulphide bonds. The short arms of the Y, with the light chains, are called the Fab (fragment antigen binding) section of the antibody. The antigen combining site lies between the open ends of the light and heavy chains. See also IgA, IgD, IgE, IgG and IgM. Some immunoglobulins are prepared as drugs for the management of RHESUS incompatibility and antibody deficiency; for the prophylaxis of MEASLES and hepatitis A; to minimize fetal damage when a pregnant woman is exposed to RUBELLA; and to assist in the treatment of TETANUS and RABIES. They are marketed under such brand names as Flebogamma, Gammabulin, Gammagard, Octagam, Rhophylac, Sandoglobulin, Vigam liquid and Winrho SDF.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005


Any of several types of globulin proteins that function as antibodies.
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
Plasma-derived medicines company Grifols (MCE:GRF) (MCE:GRF.P) (NASDAQ: GRFS) reported on Thursday the receipt of US Food and Drug Administration (FDA) approval for the new Xembify 20% subcutaneous immunoglobulin for the treatment of primary immunodeficiencies.
(iii) We recommend that patients who are on treatment for immune thrombocytopenic purpura or other autoimmune conditions with rituximab should be tested for immunoglobulins at baseline level before the treatment as well as looking for any sign of immunodeficiency before, during, and after the treatment.
Chemical composition and immunoglobulins status of colostrum and whole milk: The chemical composition and immunoglobulin levels of colostrum and milk are represented in Table 2.
In one report (7), the group captured immunoglobulins by using antisera to [kappa] and [lambda] light chains, and then reduced disulfide bonds and scanned for light chains with restricted mlz ratios.
Material and Methods: The demographic findings, clinical and laboratory findings, subcutaneous immunoglobulin dosage and dose frequency, infusion time, area and methods, adverse events and frequency of infections were obtained from patient files and recorded.
Objective: To determine and compare the serum levels of immunoglobulins (IgG, IgM, IgA) and CRP in autistic children and healthy controls.
The secretory immunoglobulins are the most essential section of the antibody-dependent defence of the body.11,12
"The immunoglobulins have different properties in obese patients.
* Serum and plasma standards, controls, purified immunoglobulins and serum proteinsenza IgG, and Diphtheria IgG
Effect of a vigorous aerobic activity, immunoglobulins G and A on the immune system; Journal of Medicine, Guilan University of Medical Sciences., 12(46).
ProteinPruTect also boosts immune function in light of stress from surgery—particularly when paired with immunoglobulin concentrate and arabinogalactan.

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