immunofixation


Also found in: Wikipedia.

immunofixation

[-fiksā′shən]
a process by which antigens in a protein mixture are separated on an electrophoretic gel and identified by the application of labeled antibodies.
References in periodicals archive ?
Contract notice: Supply of reagents and various materials for the study of proteins by electrophoresis and immunofixation for the biochemistry laboratory of the University Hospital 12 de Octubre
4) While this recommendation is relatively simple and straightforward, there is a legacy of tests that have been ordered by physicians including these three plus urine protein electrophoresis (uPEP) and urine immunofixation (uIFE).
A commercially available QuickGel Chamber with immunofixation offers a rapid, semi-automated method for separating proteins of differential electrophoretic mobility.
In this patient, the immunofixation electrophoresis of serum did not show any monoclonal gammopathy.
Immunofixation electrophoresis (IFE), traditionally a confirmatory technique, has been promoted as a first-line screen.
2 The use of Congo red staining methods to diagnose CA and further subtyping with immunofixation, serum free light chains, and mass spectrometry help differentiate light chain amyloidosis (AL) from transthyretin amyloidosis (ATTR): the two most common types of CA.
In rest of the 4 cases, band was determined by immunofixation method.
Helena offers automated gel electrophoresis systems for serum proteins, immunofixation, and cholesterol and hemoglobin analysis.
Laboratory analyses (erythrocyte sedimentation rate, complete blood count with leucocyte formula, biochemistry analyses, serum protein electrophoresis (SPEP) with immunofixation (IFX), serum angiotensin-converting enzyme (ACE));
Moreover, this sensitive immunoassay is able to detect very low concentrations of FLC (3-4mg/L) and is an effective substitute for immunofixation electrophoresis (IFE), which has an analytical sensitivity of only 100-150 mg/L of FLC, for use in the diagnosis of B- and plasma cell dyscrasias.
Detection of specific serum cryoprecipitates isolated by immunofixation is pathognomonic for this condition, provided the sample is collected in a warm tube.

Full browser ?