immunodeficiency disease


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Related to immunodeficiency disease: severe combined immunodeficiency disease, immune deficiency

immunodeficiency disease

[-difish′ənsē]
any of a group of diseases caused by a defect in the immune system and generally characterized by susceptibility to infections and chronic diseases. Such diseases are sometimes classified as B cell (antibody) deficiencies, T cell (cellular) deficiencies, combined T and B cell deficiencies, defects of cell movement, and defects of microbicidal activity. See also severe combined immunodeficiency disease.

im·mu·no·de·fi·cien·cy dis·ease

(im'yū-nō-dĕ-fish'ĕn-sē di-zēz')
A disorder or condition related to a defective or suppressed immune response.

immunodeficiency

a deficiency in the immune system, either that mediated by antibody or T lymphocytes, or both. See also agammaglobulinemia, hypogammaglobulinemia, feline immunodeficiency virus, bovine immunodeficiency virus.

acquired immunodeficiency
see immune deficiency disease.
cancer-associated immunodeficiency
in general, associated with cachexia and debilitation, and also related to the type of neoplasia. Tumor-related effects on the immune system include impaired function of lymphocytes, altered cytokine production and activation of suppressor cell functions.
combined immunodeficiency
common variable immunodeficiency
a term encompassing a heterogeneous group of syndromes, which may be inherited or acquired, characterized by recurring persistent infections and deficiencies of some of the immunoglobulin classes.
congenital immunodeficiency
see immune deficiency disease.
immunodeficiency disease
iatrogenic immunodeficiency
secondary immune deficiency disease.
severe combined immunodeficiency
X-linked immunodeficiency
an inherited form of severe combined immunodeficiency has been reported in dogs. Puppies fail to grow and die from overwhelming infections at an early age.
References in periodicals archive ?
International union of immunological societies primary immunodeficiency diseases classification committee.
For additional information on immunodeficiency disease, visit the Immune Deficiency Foundation at www.
Harnessing the strength of a natural process that repairs damage to the human genome, doctors at the University of Texas Southwestern Medical Center, Dallas, have helped establish a method of therapy that can correct mutations in the IL-2R gene that is associated with the immunodeficiency disease SCID.
Parents of about 20 children suffering from the disease met to share ideas on how to care for youngsters with primary immunodeficiency disease.
However, this obstacle remains formidable, since there is currently no screening for any primary immunodeficiency disease at birth or during childhood or adulthood in any country.
In 1995, 13-month-old Layne LaRue died from a rare immunodeficiency disease called X-linked lymphoproliferative syndrome.
Doctors discovered Rhys had Xlinked severe combined immunodeficiency disease, which affects only 100 children in the UK.
Three products are currently marketed which utilize Enzon's technology: PEG-INTRON marketed by Schering-Plough for hepatitis C, ONCASPAR(R) for Acute Lymphoblastic Leukemia (ALL), and ADAGEN(R) a treatment for a form of Severe Combined Immunodeficiency Disease (SCID), commonly known as the "Bubble Boy Disease.
Alain Fischer described the outcomes in five patients who were the first to undergo successful gene therapy in the treatment of their severe combined immunodeficiency disease.
SAN FRANCISCO -- Results of separate phase I trials using gene therapy offered hope in the treatment of hemophilia A and severe combined immunodeficiency disease, investigators reported at the annual meeting of the American Society of Hematology
ADMA is pursuing an indication for the use of this IGIV product for treatment of Primary Immunodeficiency Disease, or PIDD.
US-based biotechnology company X4 Pharmaceuticals has initiated a Phase 2/3 study with the first patient dosed with X4P-001-LD for the treatment of WHIM syndrome, a sub-type of a primary immunodeficiency disease characterised by warts, hypogammaglobulinemia, infections, and myelokathexis or "WHIM," the company said.

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