The pipeline of ADCs and immunoconjugates
in advanced clinical development gives the chance of approval of further ADCs in the near- and mid-term future.
Cytotoxic properties of immunoconjugates
containing melittin-like peptide 101 against prostate cancer: in vitro and in vivo studies.
Their topics include the humanization of antibodies, affinity maturation approaches for antibody lead optimization, antibody expression from bacteria to transgenic animals, the design and application of immunoconjugates
for cancer therapy, and dual-targeting bispecific antibodies as new therapeutic modalities for cancer.
Use of elevated temperature and optimized pH to achieve high specific activity and high chelate stability in radiolabeled immunoconjugates
Targeted therapy of cancer: New prospects for antibodies and immunoconjugates
Appropriate testing with different dilutions of the antigens, sera, and immunoconjugates
Genistein--bovine serum albumin (BSA) immunoconjugates
were synthesized by addition of 2.
The new immunoconjugates
can be used in tumor therapy.
The corporation produces cGMP paclitaxel and is building a platform of other taxane-based drug candidates such as taxane analogs, proprietary formulations and immunoconjugates
targeting various cancers and multi-drug resistant tumors.
This partnership will allow the development of immunoconjugates
able to attack the cells involved in metastasis in invasive breast and pancreas cancers.
These are examples of immunoconjugates
Key Topics Covered: 1 Executive Summary 2 Introduction and Overview of the Report 3 Antibody-Drug Conjugates: Pipeline Description and Analysis 4 Stakeholders in Antibody-Drug Conjugates and Immunoconjugates
5 ADC Technologies 6 Business with Antibody-Drug Conjugates 7 ADC & Immunoconjugate
Company Profiles 8 References 9 Tables Companies Mentioned: