immunoconjugates

immunoconjugates

monoclonal antibodies which are target-specific carriers for specific compounds such as plant or bacterial toxins, radionuclides, photoactive agents and chemotherapeutic drugs.
References in periodicals archive ?
The pipeline of ADCs and immunoconjugates in advanced clinical development gives the chance of approval of further ADCs in the near- and mid-term future.
Cytotoxic properties of immunoconjugates containing melittin-like peptide 101 against prostate cancer: in vitro and in vivo studies.
Their topics include the humanization of antibodies, affinity maturation approaches for antibody lead optimization, antibody expression from bacteria to transgenic animals, the design and application of immunoconjugates for cancer therapy, and dual-targeting bispecific antibodies as new therapeutic modalities for cancer.
Use of elevated temperature and optimized pH to achieve high specific activity and high chelate stability in radiolabeled immunoconjugates," Bioconjug.
Targeted therapy of cancer: New prospects for antibodies and immunoconjugates.
Appropriate testing with different dilutions of the antigens, sera, and immunoconjugates was conducted.
The new immunoconjugates can be used in tumor therapy.
The corporation produces cGMP paclitaxel and is building a platform of other taxane-based drug candidates such as taxane analogs, proprietary formulations and immunoconjugates targeting various cancers and multi-drug resistant tumors.
This partnership will allow the development of immunoconjugates able to attack the cells involved in metastasis in invasive breast and pancreas cancers.
These are examples of immunoconjugates and bioconjugates.
Key Topics Covered: 1 Executive Summary 2 Introduction and Overview of the Report 3 Antibody-Drug Conjugates: Pipeline Description and Analysis 4 Stakeholders in Antibody-Drug Conjugates and Immunoconjugates 5 ADC Technologies 6 Business with Antibody-Drug Conjugates 7 ADC & Immunoconjugate Company Profiles 8 References 9 Tables Companies Mentioned: