an autoantibody, usually of the immunoglobulin M class, that is specific for activated C3 and C4 components of complement. It is found in low titer in most normal sera and in increased levels in certain infectious diseases, in autoimmune disease, and after immunization with many antigens.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
An autoantibodylike immunoglobulin (IgM), formed in animals or humans against their own complement following injection of complement-containing complexes or sensitized bacteria.
Farlex Partner Medical Dictionary © Farlex 2012
An autoantibodylike immunoglobulin (IgM) formed by an organism against its own complement, following injection of complement-containing complexes or sensitized bacteria.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012