immunocomplex


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complex

 [kom´pleks]
1. the sum, combination, or collection of various things or related factors, like or unlike; e.g., a complex of symptoms (see syndrome).
2. a group of interrelated ideas, mainly unconscious, that have a common emotional tone and strongly influence a person's attitudes and behavior.
3. that portion of an electrocardiographic tracing which represents the systole of an atrium or ventricle.
AIDS-related complex (ARC) a complex of signs and symptoms occurring in HIV infection including fever, weight loss, prolonged diarrhea, minor opportunistic infections, lymphadenopathy, and changes in cells of the immune system.
antigen-antibody complex here the complex formed by the noncovalent binding of an antibody and antigen. Complexes of antibodies belonging to certain immunoglobulin classes may activate complement. Called also immune complex.
anti-inhibitor coagulant complex (AICC) a concentrated fraction from pooled human plasma, which includes various coagulation factors. It is administered intravenously as an antihemorrhagic in hemophilic patients with inhibitors to coagulation factor VIII.
atrial complex the P wave of the electrocardiogram, representing electrical activity of the atria. See also ventricular complex.
castration complex in psychoanalytic theory, unconscious thoughts and motives stemming from fear of loss of the genitals as punishment for forbidden sexual desires.
Electra complex libidinous fixation of a daughter toward her father. This term is rarely used, since oedipus complex is generally applied to both sexes.
factor IX complex a sterile, freeze-dried powder consisting of partially purified coagulation factor IX fraction, as well as concentrated factor II, VII, and X fractions, of venous plasma from healthy human donors. It is used in the prophylaxis and treatment of bleeding in patients with hemophilia B, replacement of factor VII in patients deficient in that factor, and treatment of anticoagulant-induced hemorrhage. Administered intravenously.
Ghon complex primary complex (def. 1).
Golgi complex golgi apparatus.
HLA complex the human major histocompatibility complex, which contains the hla antigens.
immune complex antigen-antibody complex.
inclusion complex one in which molecules of one type are enclosed within cavities in the crystalline lattice of another substance.
inferiority complex unconscious feelings of inadequacy, producing shyness or timidity or, as a compensation, exaggerated agressiveness and expression of superiority; based on Alfred Adler's concept that everyone is born with a feeling of inferiority stemming from real or imagined physical or psychological deficiency, with the manner in which the inferiority is handled determining behavior.
interpolated premature ventricular complex a premature ventricular complex that does not interfere with the conduction of the next sinus beat, i.e., it lacks the usual following compensatory pause.
major histocompatibility complex (MHC) the chromosomal region containing genes that control the histocompatibility antigens; in humans it controls the hla antigens.
membrane attack complex (MAC) C5b,6,7,8,9, the five-molecule complex that is the cytolytic agent of the complement system.
Oedipus complex see oedipus complex.
primary complex
1. the combination of a parenchymal pulmonary lesion (Ghon focus) and a corresponding lymph node focus, occurring in primary tuberculosis, usually in children. Similar lesions may also be associated with other mycobacterial infections and with fungal infections.
2. the primary cutaneous lesion at the site of infection in the skin, e.g., chancre in syphilis and tuberculous chancre.
QRS complex a group of waves seen on an electrocardiogram, representing ventricular depolarization. Called also QRS wave. It actually consists of three distinct waves created by the passage of the cardiac electrical impulse through the ventricles and occurs at the beginning of each ventricular contraction. In a normal surface electrocardiogram the R wave is the upward deflection; the first downward deflection represents a Q wave and the final downward deflection is the S wave. The Q and S waves may be extremely weak and sometimes are absent.

One abnormality of the QRS complex is increased voltage resulting from enlargement of heart muscle, which produces increased quantities of electric current. A low-voltage QRS complex may result from toxic conditions of the heart, most commonly from fluid in the pericardium. Pleural effusion and emphysema also can cause a decrease in the voltage of the QRS complex.
VATER complex an association of congenital anomalies consisting of vertebral defects, imperforate anus, tracheoesophageal fistula, and radial and renal dysplasia.
ventricular complex the Q, R, S, and T waves of the electrocardiogram, representing ventricular electrical activity. See also atrial complex.

im·mune com·plex

antigen combined with specific antibody, to which complement may also be fixed. It may precipitate or remain in solution. Frequently associated with autoimmune disease.
Synonym(s): immunocomplex
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References in periodicals archive ?
ESTABLISHMENT OF mAbs TARGETING THE HAPTEN-ANTIBODY IMMUNOCOMPLEX
It involves linkage between the antigen & a membrane-bound antibody to form an immunocomplex that is later revealed through a colorimetric reaction.
The presence of a specific immunocomplex on the solid phase was detected by the action of the captured conjugate on the chromogen in the second incubation.
The first reaction involves interaction between vitamin D in the sample to vitamin D-specific ruthenium labelled antibody to form an immunocomplex. Biotinylated vitamin D and streptavidin-coated microparticles are added in the second reaction.
The amount of peroxidase retained in the immunocomplex was determined photometrically by incubating with 2,2'-azino-di-[3- ethylbenzthiazoline sulfonate] (ABTS) as a substrate for 10 min at 20[degrees]C.
The mechanism of flavonoid-induced ARF is uncertain but may be associated with hemolysis, DIC, and autoimmune and immunocomplex mechanisms.
Due to the high specificity of the interaction, little frequency change is observed unless the antigen-antibody immunocomplex is formed.
After 7, 16, and 24 h, the cells were lysed in 200 [micro]l of lysis buffer, and 20 [micro]l of the supernatant was reacted with 80 [micro]l of anti-DNA immunocomplex conjugated with peroxidase, which interacts with streptavidin-coated wells, in a microtiter plate for 2 h.
To measure the activity of STEP, we immunoprecipitated the protein by a specific antibody and evaluated the phosphatase activity associated with the immunocomplex. As shown in Figure 3(b), STEP activity was downregulated in [SOD1.sup.G93A], both in the cortex and in the spinal cord (58.7 [+ or -] 5.9% and 63.7 [+ or -] 7.4% of reduction, resp., p < 0.05 with respect to controls, Mann-Whitney U test).
The detection limit of 4 ng immunocomplex is obtained using SiNWs-AgNPs as SERS substrate.
[161] described classification of otologic involvement into 5 distinct patterns: (1) serous otitis media, the most common (90%), resulting from Eustachian tube obstruction and nasopharyngeal involvement; (2) SNHL (43%) due to vasculitis of the cochlear vessels and the immunocomplex deposits in the cochlea; (3) chronic otitis media (24%) caused by middle ear mucosa lesions; (4) vertigo resulting from central system involvement and immunocomplex deposits in the vestibular portion of the inner ear; and (5) facial nerve palsy (8%) usually associated with otitis media, secondary to compression of the nerve in the middle ear course, especially in the presence of dehiscence in the fallopian canal.