Moreover, histopathologic features (ie, paracortical expansion, immunoblastic
proliferation, necrosis in paracortex, predominance of T cells, and circulating atypical/reactive lymphocytes in the peripheral blood) are similar to those seen in viral infections.
The common morphological subtypes are centroblastic, immunoblastic
, and anaplastic.
PC-ALCL is a CD30+ lymphoproliferative disorder of the skin consisting of cells with an anaplastic, pleomorphic, or immunoblastic
cytomorphology with > 75% of the tumor cells expressing CD30 (Ki1) antigen.
lymphoma, large B, diffuse, and immunoblastic
) and anatomically located in the stomach (ICD-O-3 topography code: C16).
The histopathological assessment of the tissue revealed diffuse proliferation of large monomorphic atypical lymphoid cells admixed with few medium-sized cells (centroblastic and prominent immunoblastic
lymphoid cells) (Figure 5).
One review of all reported cases [n = 40] between 1995 and 2002 demonstrated that the majority of primary cardiac lymphomas are diffuse large cell (60%), with the second most common being large cell (5%), immunoblastic
(5%), lymphoblastic (5%), diffuse medium-cell (5%), diffuse small-cell (5%), and diffuse (5%) .
Other differential diagnoses included secondary cutaneous plasmacytoma in the setting of systemic disease, mucosal extramedullary plasmacytoma with secondary skin involvement, marginal zone B-cell lymphoma, plasma cell granuloma, non-Hodgkin lymphoma, high-grade malignant immunoblastic
lymphoma, and poorly differentiated neoplasms, as well as infectious diseases that cause infiltration of plasma cells.
The presence of immunoblastic
or plasmablastic morphology in a suspected hematolymphoid neoplasm should prompt investigation of a differential diagnosis that includes large B-cell lymphoma arising in HHV8-associated MCD and primary effusion lymphoma [11, 12].
Of the 3 patients opting out of study, 02 had evidence of disease on ultrasonography and 01 patient had CNS relapse (Infiltration by high-grade immunoblastic
lymphoma), who expired after two months.
This term refers to the development of an aggressive non-Hodgkin's lymphoma (diffuse large cell or immunoblastic
) when during the course of CLL appear an abrupt clinical deterioration with worsening systemic symptoms rapid tumor growth and/or extranodal involvement.
The combination of drugs rather than a single agent was implicated for drug-induced pancreatitis in a previous case report that described the development of acute pancreatitis shortly after the second cycle of the chemotherapy regimen composed of cyclophosphamide, doxorubicin, and vincristine in a patient with mediastinal immunoblastic