immunoassay


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immunoassay

 [im″u-no-as´a]
any of several methods for the quantitative determination of chemical substances, such as hormones, drugs, and specific proteins, that utilize the highly specific binding between an antigen or hapten and homologous antibodies, including radioimmunoassay, enzyme immunoassay, and fluoroimmunoassay.

im·mu·no·as·say

(im'yū-nō-as'ā, im-yū'nō),
Detection and assay of substances by serologic (immunologic) methods; in most applications the substance in question serves as antigen, both in antibody production and in measurement of antibody by the test substance.
See also: enzyme-linked immunosorbent assay, radioimmunoassay, radioimmunoelectrophoresis, immunologic pregnancy test.

immunoassay

(ĭm′yə-nō-ăs′ā, ĭ-myo͞o′-)
n.
A laboratory technique that identifies and quantifies a protein, such as a hormone or an enzyme, based on its ability to act as an antigen or antibody in a chemical reaction.

immunoassay

Lab medicine Any assay that measures an antigen-antibody response, the sensitivity of which varies according to the method; an immunologic test that quantifies a particular antigen using a cognate antibody. See ELISA, RIA.

im·mu·no·as·say

(im'yū-nō-as'ā)
Detection and assay of substances by serologic (immunologic) methods.
See also: radioimmunoassay, radioimmunoelectrophoresis, immunologic pregnancy test
Synonym(s): immunochemical assay.

immunoassay

A method of testing for, and measuring the concentration of, various antibodies. Various methods, including RADIOIMMUNOASSAY, enzyme linked immunosorbent assay (ELISA) and immunoelectrophoresis may be used.

immunoassay

an assay of a substance that is based on its reaction with a specific ANTIBODY. See, for example, ELISA.

im·mu·no·as·say

(im'yū-nō-as'ā)
Detection and assay of substances by serologic (immunologic) methods; in most applications substance in question serves as antigen, both in antibody production and in measurement of antibody by the test substance.
References in periodicals archive ?
This report mentions various factors that are causative of fast-paced expansion of the Immunoassays in R&Dmarket.
A / IN ADULTS TREATED with opioids for chronic pain, point-of-care (POC) urine drug screens (immunoassays) for detecting opioids show a false-negative rate of 1.9%, a sensitivity of 92%, and a specificity of 93% compared with the gold-standard liquid chromatography tandem mass spectrometry (LC-MS).
(5) Healthy study participants who consumed 15 mg to 30 mg of biotin daily were shown to have biotin concentrations of over 30 ng/mL; these levels could interfere with biotin-based immunoassays. (6)
The stepwise miRNA assay protocol is much slower than routine simultaneous incubation sandwich immunoassays (e.g., sandwich immunoassays performed on the Advia Centaur[R] analyzer used in this work only require 7.5-min incubations).
B, Comparison of 125 PSA serum measurements made with Roche cobas immunoassay (Roche Diagnostics, Indianapolis, Indiana) versus the MS PSA assay.
The other, published April 20 in Analytical Chemistry, demonstrates the effect in immunoassays. In addition to Chou, the authors include post-doctoral researchers Weihua Zhang, Liangcheng Zhou and Jonathan Hu and graduate students Fei Ding, Wei Ding, Wen-Di Li and Yuxuan Wang.
Protein microarray glass slides utilizing the PATH technology are also available from leading life science consumable suppliers to enable researchers to perform ultra sensitive assays including sandwich immunoassays, capture immunoassays, protein profiling, and protein characterization.
Because pregnancy increases levels of thyroid binding proteins, a free [T.sub.4] immunoassay to confirm an abnormal TSH level in pregnancy "is not as reliable because of these biological changes," he said.
Free [T.sub.4] immunoassays aren't reliable in subgroups of patients with disturbances in binding proteins, Dr.
Each was detected in a bacteria-specific lateral flow immunoassay strip to evaluate the ability of SEL to facilitate the detection of several foodborne pathogens simultaneously.
The authors indicated that technologic advances have improved the specificity of detecting SV40 antibodies and used an enzyme immunoassay based on viruslike particles (VLPs) to perform the analysis (1).
today announced their conclusion of a joint research agreement for development of a new KL-6 test kit consisting of an in-vitro, supplementary diagnostic marker for interstitial pneumonia compatible with LUMIPULSE (automatic chemiluminescent enzyme immunoassay) systems.