immunoablative

immunoablative

 [im″mu-no-ab´lah-tiv]
immunosuppressant with removal and destruction of a cell population, such as in the ablative step preceding bone marrow transplantation.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
References in periodicals archive ?
Aymeric et al., "Cancer-induced immunosuppression: IL-18-elicited immunoablative NK cells," Cancer Research, vol.
Following immunoablative therapy, ACPA-IgG of low avidity developed again which suggested a newly generated autoimmune response [103].
Verpoortet al., "Differential responsiveness to immunoablative therapy in refractory rheumatoid arthritis is associated with level and avidity of anti-cyclic citrullinated protein autoantibodies: a case study," Arthritis Research & Therapy, vol.
After receiving an autologous stem cell transplant (SCT), she experienced a relapse of disease and was enrolled in an experimental protocol of immunoablative chemotherapy, followed by hematopoietic SCT at the National Institutes of Health Clinical Center in Bethesda, Maryland (www.ClinicalTrials.gov identifier NCT00520130).
The authors concluded that this immunoablative regimen of cyclophosphamide for patients with aggressive MS was safe, worthy of further study and may be an alternative to bone marrow transplantation.
A key to the success of this program is that patients receive a conditioning regimen that is immunoablative but not myeloablative.
The use of G-CSF did not induce inflammatory activity in the central nervous system; CNS antibody production decreased after immunoablative therapy.