immunoablation

immunoablation

(ĭm-ū″-nō-ă-blā′shŭn)
The systematic destruction of a patient's immune competence. Immunoablation is used to prepare patients for organ transplantation and to treat refractory autoimmune diseases, esp. when followed by immunoreconstruction (usually with autologous stem cell transplantation).

Patient care

Patients who have undergone immunoablation may be easily infected by caregivers. Careful handwashing and infection control techniques (such as “reverse isolation”) should be used to limit exposing these patients to harmful pathogens.

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References in periodicals archive ?
The conditioning regimens are administered as part of the procedure to achieve two goals: provide sufficient immunoablation to prevent graft rejection and reduce the tumor burden.
Torosian et al., "Independence of exogenous insulin following immunoablation and stem cell reconstitution in newly diagnosed diabetes type I," Bone Marrow Transplantation, vol.
The trial evaluated a treatment called immunoablation and autologous hematopoietic stem cell transplantation (IAHSCT).