An unproven method for cancer management developed in the 1980s by an American biochemist, L Burton, which was based on the assertion that the immune system is enhanced by four substances present in tissue: “blocking” and “deblocking” proteins, tumour antibody and “complement” (which differs from complement as used by immunologists). IAT consists of parenteral administration of tumour cell lysates and serum from cancer patients and normal subjects. It is not FDA approved—there is no scientific evidence of IAT’s efficacy and its safety is questionable, as culture of the sera used has revealed bacterial contamination. IAT has been administered in clinics in the Bahamas, Mexico and Germany.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.