[USA], Apr 20 (ANI): A research conducted on mice discovered that having too much molecular switch called VGLL3, which regulates immune response genes
in skin cells, lead to autoimmune diseases.
However, MN is most likely more complex, involving several antigen-antibody systems and immune response genes
. To get a comprehensive view of self and food/environmental antigenic targets and of HLA and non-HLA trigger genes, and to design new rapidly acting therapies, I will develop novel technological approaches such as immunopeptidomics, and explore new pathophysiological and therapeutic concepts with 3 major objectives:1.
Rather than one single gene being responsible for cervical carcinogenesis, the authors postulate that variations in the different immune response genes
lead to subtle differences in the effectiveness of the antiviral and antitumor immune responses, ultimately leading to differences in risk of developing cervical cancer and progressive disease after HPV infection.
PCR amplification of selected immune response genes
They found that in helper T (CD4+) cells, the proteins Oct1 and OCA-B work together to put immune response genes
on standby so that they are easily activated when the body is re-exposed to a pathogen.
Chronic exposure to arsenic in the drinking water alters the expression of immune response genes
in mouse ung.
Association of Marek's disease with Ea-B and immune response genes
in subline and F2 populations of the Iowa State S1 Leghorn line.
The sequence of dirucotide is associated with the autoimmune process in MS patients with certain immune response genes
(HLA types DR2 and/or DR4); MS patients having these genes represent approximately 70 percent of all MS patients.
Fewer copies of specific immune response genes
may increase an individual's risk of contracting HIV and AIDS.
This is thought to ensure that their offspring have as wide a range of immune response genes
- and therefore greater protection against infection - as possible.
A cluster of immune response genes
called the Major Histocompatibility Complex (MHC) is known to influence pheromones in animals and humans.
Because of these shared immune response genes
, changes in the microbiome, and other environmental factors, the host immune response to EBV and other herpes viruses may be evolving unpredictably with the host immune response (Figure 1).