[USA], Apr 20 (ANI): A research conducted on mice discovered that having too much molecular switch called VGLL3, which regulates
immune response genes in skin cells, lead to autoimmune diseases.
Rather than one single gene being responsible for cervical carcinogenesis, the authors postulate that variations in the different
immune response genes lead to subtle differences in the effectiveness of the antiviral and antitumor immune responses, ultimately leading to differences in risk of developing cervical cancer and progressive disease after HPV infection.
PCR amplification of selected
immune response genes in PBMCs
They found that in helper T (CD4+) cells, the proteins Oct1 and OCA-B work together to put
immune response genes on standby so that they are easily activated when the body is re-exposed to a pathogen.
Chronic exposure to arsenic in the drinking water alters the expression of
immune response genes in mouse ung.
Association of Marek's disease with Ea-B and
immune response genes in subline and F2 populations of the Iowa State S1 Leghorn line.
The sequence of dirucotide is associated with the autoimmune process in MS patients with certain
immune response genes (HLA types DR2 and/or DR4); MS patients having these genes represent approximately 70 percent of all MS patients.
Fewer copies of specific
immune response genes may increase an individual's risk of contracting HIV and AIDS.
This is thought to ensure that their offspring have as wide a range of
immune response genes - and therefore greater protection against infection - as possible.
A cluster of
immune response genes called the Major Histocompatibility Complex (MHC) is known to influence pheromones in animals and humans.
Because of these shared
immune response genes, changes in the microbiome, and other environmental factors, the host immune response to EBV and other herpes viruses may be evolving unpredictably with the host immune response (Figure 1).