immune reconstitution

immune reconstitution

The restoration of normal or improved immune function in a person with congenital or acquired immunodeficiency syndrome. Bone marrow transplantation or drug therapies may be used, depending on the underlying cause of the immune failure.
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Mavenclad is a selective immune reconstitution therapy that simplifies treatment administration by giving patients just 2 short annual courses of tablets with a maximum of 20 days of treatment over 2 years providing a lasting treatment benefit up to 4 years.
We had an immune reconstitution inflammatory syndrome in 4 patients (1.
Results from 47 patients demonstrated that administering BPX-501 following an alpha/beta T-cell depleted haploidentical hematopoietic stem cell transplant (alpha/beta T-cell depleted haplo-HSCT) produced rapid immune reconstitution, low incidence of acute and chronic Graft versus Host Disease (GvHD), and a low rate of disease relapse.
described hypercalcemia presenting as part of the spectrum of immune reconstitution inflammatory syndrome (IRIS) against MAI.
Baseline CD4+ T-cell count >200 cells/mm[sup]3 in comparison to CD4+ T-cell count ≤200 cells/mm[sup]3 was associated with more complete immune Reconstitution (77.
Molecular defects in human severe combined immunodeficiency and approaches to immune reconstitution.
But some lesions especially oral warts related to human papilloma virus (HPV) and oral ulcers, xerostomia, mucositis, hyperpigmentation, erythema multiforme and lichenoid reactions have been reported to be increased after ART attributed to the immune reconstitution, adverse effects of ART or drug resistance.
After 3 weeks of therapy, she began taking oral dexamethasone (2 mg 4x/d) to reduce intracranial pressure and control symptoms consistent with immune reconstitution inflammatory syndrome.
This prompted consideration of the Guillain-Barre syndrome (GBS) variant of neurological immune reconstitution inflammatory syndrome (IRIS).
At that time, diagnosis of lower respiratory system infection in the setting of PCP-related immune reconstitution inflammatory syndrome (PCP-IRIS) was most probable due to negative microbiological tests and rapid restoration of immunity.
The introduction of highly active antiretroviral treatment (HAART) has led to the emergence of a new clinical syndrome, immune reconstitution inflammatory syndrome (IRIS).