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the type of hemolysis caused by complement when erythrocytes have been sensitized by specific complement-fixing antibody.
Synonym(s): conditioned hemolysis
the destruction of red blood cells caused by the formation of specific antigen-antibody complexes in the presence of complement.
1. being highly resistant to a disease because of the formation of humoral antibodies or the development of immunologically competent cells, or both, or as a result of some other mechanism, such as interferon activities in viral infections.
2. characterized by the development of antibodies or cellular immunity, or both, following exposure to antigen.
3. produced in response to antigen, such as immune serum globulin. The essential feature of antibody and cell-mediated immunity is that they are highly antigen specific.
the binding of antibody-antigen-complement complexes to complement receptors found on red blood cells.
see antibody-antigen complex.
immune complex disease
immune complex reaction
type III hypersensitivity (1).
immune deficiency disease
one in which animals have inadequate immune responses and so are more susceptible to infectious disease. The defect may be primary (inherited), or secondary (acquired) which usually develops after birth because of toxins or infectious agents. See also combined immune deficiency syndrome, hypogammaglobulinemia, agammaglobulinemia, inherited parakeratosis, chediak-higashi syndrome and canine granulocytopathy syndrome.
see immune-mediated hemolytic anemia (below).
immune reaction fever
aseptic fever occurring in anaphylaxis, angioedema.
the specific response to substances interpreted by the body as not-self, the result being humoral and cellular immunity. The immune response depends on a functioning thymus and the conversion of stem cells to B and T lymphocytes. These B and T lymphocytes contribute to antibody production, cellular immunity and immunological memory. See also humoral immunity.
immune response (Ir) genes
see immune response genes.
the detection by lymphocytes, especially T lymphocytes, of new antigens, particularly on tumor cells.
consists of the primary lymphoid organs (thymus and Bursa of Fabricius or its equivalent (bone marrow) in mammals) and secondary lymphoid organs (lymph nodes, spleen and other lymphoid tissue).
see immunological tolerance.