autoimmune cholangitis

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autoimmune cholangitis

An autoimmune disorder displaying the clinical and histopathological features of primary biliary cirrhosis, characterised by
(1) Positive anti-nuclear antibodies and/or anti-smooth muscle antibodies,
(2) Immunofluorescence negative for anti-mitochondrial antibodies,
(3) Biochemical or histologic features of cholestatic and hepatocellular injury, and
(4) Exclusion of chronic, viral, metabolic or toxic liver disease.