immediate hypersensitivity reaction


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im·me·di·ate hy·per·sen·si·tiv·i·ty

an exaggerated immune response mediated by mast cell-bound IgE antibodies occurring within minutes after exposing a sensitized individual to the approximate antigen; also called Type I hypersensitivity. Clinical symptoms result from the physiologic effects of preformed or newly generated mediators, including histamine, platelet activating factor, prostaglandins, leukotrienes, bradykinin, tachykinins, and others. The reaction may be localized to specific organ systems or be generalized, leading to anaphylaxis. Symptoms include pruritus, urticaria, angioedema, conjunctivitis, sneezing, rhinorrhea, bronchospasm, hypotension, arrhythmias, and shock. See: allergy.

immediate hypersensitivity reaction

References in periodicals archive ?
Immediate hypersensitivity reactions to penicillin and related antibiotics.
Rare cases of urticaria, angioedema, rash, bronchospasm, anaphylaxis, and oropharyngeal edema may occur as immediate hypersensitivity reactions after administration of ipratropium bromide.
IgE has a major role in immediate hypersensitivity reactions to food antigens.
Objective clinical and laboratory studies of immediate hypersensitivity reactions to food in asthmatic children.

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