imidazole


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imidazole

 [im″id-az´ōl]
1. an organic compound in which two of the five atoms that make up the ring are nitrogen atoms. It is an antimetabolite and inhibitor of histamine and is used as an insecticide.
2. any of a class of antifungal agents that contain this compound.

im·id·a·zole

(im-id'ă-zōl),
A five-membered heterocyclic compound occurring in l-histidine and other biologically important compounds.

imidazole

(ĭm′ĭ-dăz′ōl′)
n.
1. An organic crystalline base, C3H4N2, that is an inhibitor of histamine.
2. Any of various derivatives of this compound, which often have antifungal, anthelmintic, or antibiotic properties.

im·id·a·zole

(i-mid'i-zōl)
A five-membered heterocyclic compound occurring in l-histidine and other biologically important compounds.
References in periodicals archive ?
where [H.sub.a] is the peak which is attributed to the protons adjacent to the sulfonate groups and [H.sub.b] is the peak assigned to protons next to the carbon of the imidazole group located at both the sulfonated and nonsulfonated regions.
Figure 2 shows the corrosion rate of copper after it had immersed in test solution, with or without magnetic field, for a week, while Table 1 shows the inhibition efficiency of imidazole based on the result of the weight loss test.
Hence, in this study, an attempt is made to elucidate the toxicological response of pure Imidazole following direct contact with bone marrow mesenchymal stem cells.
Black crystals, Yield (1.97 g, 90%), m.p 178-180[degrees]C, IR (KBr, [v.sub.max] in [cm.sup.-1]): 3432 (-NH), 3178 (=C-H), 1909 (C=N), 1628 (C=C), 1700 (C=O), [sup.1]H NMR (DMSO-[d.sub.6], 400 MHz) [delta] ppm: 7.09-7.13 (d, 1H, -C=CH- vinulic proton, [J.sub.H-H] = 16.4 Hz), 7.3-79 (m, 8 aryl, 4 phenyl), 8.09-8.13 (d, 1H, -CH=C-, vinylic proton, [J.sub.H-H] = 16.4 Hz), 10.2 (s, 1H, -NH of benzimidazole), [sup.13]C NMR (DMSO-[d.sub.6], 100 MHz) d ppm: 102.29, 106.24, 108.53, 110, 112, 120, 121, 122, 128.51, 129, 130, 132, 142, 148, 152, 190.91 (12 aryl carbons, 6 phenyl carbons, 2 vinylic carbons, 1 imidazole quaternary carbon and 1 carbonyl carbon), MS (m/z): 343.2 ([M.sup.+*]), Anal.
The presence of imidazole moiety and hydrogen bonding area in the title compounds 6a-p could improve their binding with the complementary receptor binding area in vivo.
Complexes 2, 3, 4, and 5 were also synthesized in a similar fashion described above as 1 by employing Me-ImH(1.0 mmol, 0.07 g); Et-ImH (1.0 mmol 0.08 g); 2-benz-ImH(1.0 m mol, 0.12 g); benz-ImH (1.0 m mol; 0.13 g), respectively, in place of imidazole (ImH).
Due to availability of pyridine and pyrrole atoms in the structure of imidazole molecules, these molecules exhibit both acid and basic properties.
These functional groups are sulfhydryl (SH), alcohol (OH), imidazole, cyano (CN), and azide ([N.sub.3]) which areabletointeractasLewis-base in the coordination of the catalytic zinc ion.
The imidazole antifungal agent clotrimazole has been widely used topically for the treatment of superficial dermatophytosis for a long time.4,5
Lower concentrations of imidazole are required during purification, which better preserves the structure and function of sensitive proteins.
coli cells using affinity chromatography were optimized to determine the ideal arabinose, imidazole and NaCl concentrations.
If you have been prescribed metronidazole (Flagyl) or imidazole (Tindamax), avoid consuming alcohol until 72 hours after you've completed the course.