This type of Crohn's disease is called ileocolitis
Thirty healthy subjects, 13 males and 17 females (ages, 0.4-13 years; mean, 7.4 years) were enrolled as controls; 10 patients with Crohn's ileocolitis
(ages, 13.2-21 years; mean, 14.7 years) and 10 patients with coeliac disease (ages, 1.3-17.9 years; mean, 5.8 years), in the moderate or severe activity phases of their diseases, were also enrolled.
The most common symptom is pruritus in the perianal region, but infestation may also present with ileocolitis
, enterocutaneous fistula, urinary tract infection, mesenteric abscesses, salpingitis and appendicitis.
Three patients with ileitis, 15 patients with ileocolitis
, and 22 patients with colitis were enrolled in CD group.
Cobalamin malabsorption at the terminal ileum is linked to acid pH, often due to pancreatitis, lactose, dysbiosis, or ileocolitis
. Folic acid deficiency is most often due to gluten enteropathy, MTHFR (methylenetetrahydrofolate reductase) mutation and/or ingested oxidants, especially chloramines and fluoride.