Also found in: Dictionary, Acronyms, Encyclopedia, Wikipedia.
A pyrimidine analogue that produces both antiviral and anticancer effects by interference with DNA synthesis; a topical agent used to treat viral keratitis.
idoxuridine/idox·ur·i·dine/ (i″doks-u´rĭ-dēn) an analogue of pyrimidine that inhibits viral DNA synthesis; used as an antiviral agent in the treatment of herpes simplex keratitis.
an ophthalmic antiviral.
indication It is prescribed for the treatment of herpes simplex keratitis.
contraindications Deep ulceration of the cornea or known hypersensitivity to this drug prohibits its use.
adverse effects Among the more serious adverse effects are visual disturbances and eye discomfort.
idoxuridineVirology A topical antiviral available in an ophthalmic solution for treating herpetic and other viral infections of the cornea
A pyrimidine analogue that produces both antiviral and anticancer effects by interference with DNA synthesis; a topical agent.
idoxuridineA drug effective against herpes simplex viruses. Idoxuridine is chemically very similar to thymine, which it replaces in the viral DNA thereby preventing replication. The drug is on the WHO official list. A brand name for a preparation for external use is Herpid.
idoxuridine; Herpid topical 5% idoxuridine in dimethyl sulphfoxide; for treatment of herpes simplex or herpes zoster infections
Pyrimidine analogue that produces both antiviral and anticancer effects; topical agent used to treat viral keratitis.
a pyrimidine analog that prevents replication of DNA viruses; used topically in infection by herpesviruses.