We reviewed the electronic Mayo Clinic medical record and our own prospectively maintained internal subglottic stenosis database to identify cases of idiopathic subglottic stenosis. In this study, we only included patients with ISS who had undergone a pH impedance study.
Assessment of Severity of Idiopathic Subglottic Stenosis. The severity of the airway stenosis in patients with idiopathic subglottic stenosis was assessed by pulmonary function testing.
However, idiopathic subglottic stenosis is rare, and performing adequately powered prospective clinical or randomized studies is challenging.
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Mizuta et al., "Idiopathic subglottic stenosis is associated with activation of the inflammatory IL-17A/IL-23 axis," Laryngoscope, vol.
Johnston, "Evidence of extraesophageal reflux in idiopathic subglottic stenosis," Laryngoscope, vol.
Dailey, "Endoscopic management of idiopathic subglottic stenosis," Annals of Otology, Rhinology & Laryngology, vol.
DePew et al., "Idiopathic subglottic stenosis: an evolving therapeutic algorithm," Laryngoscope, vol.
