idiopathic midline destructive disease

idiopathic midline destructive disease

Lethal midline granuloma of Stewart A diagnosis of exclusion–criteria, consist of a midline granuloma of unknown etiology which, unlike most granulomas of the midline, are secondary manifestations of a primary process–eg, vasculitis–eg, Wegener's granulomatosis, malignancy–eg, lymphoma, nasal carcinoma, infections–eg, destructive fungal infections in immunocompromised Pts Treatment RT. See Lethal midline granuloma, Midline granuloma.

Idiopathic midline destructive disease

1. Local destruction of upper respiratory tract

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2. No progression to system disease–average follow-up, 7 years

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3. Acute/chronic inflammation with variable necrosis, without vasculitis, atypia or malignancy

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4. No evidence of infection or malignancy  

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McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.