idiopathic hypogonadotropic hypogonadism


Also found in: Acronyms.

idiopathic hypogonadotropic hypogonadism

An inherited condition (OMIM:146110) characterised by a deficiency of the pituitary secretion of FSH and luteinising hormone, impairing pubertal maturation and reproductive function.
References in periodicals archive ?
Hayes, "The fertile eunuch variant of idiopathic hypogonadotropic hypogonadism: spontaneous reversal associated with a homozygous mutation in the gonadotropin-releasing hormone receptor," The Journal of Clinical Endocrinology & Metabolism, vol.
Beranova, "Prevalence, phenotypic spectrum, and modes of inheritance of gonadotropin-releasing hormone receptor mutations in idiopathic hypogonadotropic hypogonadism," The Journal of Clinical Endocrinology & Metabolism, vol.
Normosmic Idiopathic Hypogonadotropic Hypogonadism (nIHH) Associated Genes
Molecular defects of the GnRH receptor gene in Chinese patients with idiopathic hypogonadotropic hypogonadism and the severity of hypogonadism.
Crowley, "Osteoporosis in men with idiopathic hypogonadotropic hypogonadism," Annals of Internal Medicine, vol.
The genetic and molecular basis of idiopathic hypogonadotropic hypogonadism. Nat Rev Endocrinol 2009;5:569-576.
Dwyer et al., "Reversal of idiopathic hypogonadotropic hypogonadism," The New England Journal of Medicine, vol.
GNRH1 mutations in patients with idiopathic hypogonadotropic hypogonadism. Proc.
(1) Idiopathic hypogonadotropic hypogonadism (IHH) is a condition characterized by failure to undergo puberty in the setting of low sex steroids and low gonadotropins and is due to abnormal secretion or action of the master reproductive hormone gonadotropin-releasing hormone (GnRH).
Kaiser, "The genetic and molecular basis of idiopathic hypogonadotropic hypogonadism," Nature Reviews Endocrinology, vol.
Normosmic idiopathic hypogonadotropic hypogonadism (IHH) is characterized by failure to develop secondary sexual characteristics and a mature reproductive system due to defects in the central part of the hypothalamo-pituitary-gonadal axis.
Atabekoglu et al., "Serum anti-Mullerian hormone levels correlate with ovarian response in idiopathic hypogonadotropic hypogonadism," Journal of Assisted Reproduction and Genetics, pp.
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