idiopathic dilated cardiomyopathy


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idiopathic dilated cardiomyopathy

Cardiology '…primary myocardial disease of unknown cause characterized by left ventricular or biventricular dilatation (sic) and impaired myocardial contractility'. See Actin, Dilated cardiomyopathy.

idiopathic dilated cardiomyopathy

Abbreviation: IDC
Cardiomyopathy of occult or uncertain cause, possibly due to viral infections, unrecognized toxic exposures, or a genetic predisposition, but not to ischemia, hypothyroidism, hypertension, valvular disease, or alcohol abuse.

Treatment

General supportive therapy includes rest, weight control, abstinence from tobacco, and moderate exercise at a level that does not cause symptoms. A salt-restricted diet is recommended. Therapy includes the use of vasodilators, such as ACE inhibitors, and diuretics like furosemide. Anticoagulants are important to prevent thrombus formation. IDC is a principal indication for cardiac transplant.

See also: cardiomyopathy
References in periodicals archive ?
Idiopathic dilated cardiomyopathy. An immunologic, genetic, or infectious disease, or all of the above?
He was diagnosed as having idiopathic dilated cardiomyopathy. Cardiac Resynchronisation Therapy Defibrillator (CRT-D) implantation was applied in another cardiac centre, but his rhythm was still of atrial fibrillation.
(6.) Fuster V, Gersh BJ, Giuliani ER, Tajik AJ, Brandenburg RO, Frye RL.The natural history of idiopathic dilated cardiomyopathy. Am J Cardiol 1981; 47(3): 525-30
Clinical course and risk profile in adolescents with idiopathic dilated cardiomyopathy. Am J Cardiol 2010;105(5):716-720.
Long-term efficacy and safety of coenzyme Q10 therapy for idiopathic dilated cardiomyopathy. Am J Cardiol.
Natriuretic peptides in patients with diastolic dysfunction due to idiopathic dilated cardiomyopathy. Eur Heart J 1999;20:1415-23.
The drug pentoxifylline has been demonstrated to inhibit proinflammatory cytokines and has beneficial effects on New York Heart Association (NYHA) functional class, left ventricular ejection fraction and markers of apoptosis in patients with idiopathic dilated cardiomyopathy (28,29).
In conclusion, primary idiopathic dilated cardiomyopathy was the most probable cause in this case.
Objective: We aimed to evaluate coronary blood flow by means of the TIMI (Thrombolysis in Myocardial Infarction) frame count in patients with idiopathic dilated cardiomyopathy who had angiographically proven normal coronary arteries and compare the results with those of healthy subjects.

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