idiopathic ataxia

idiopathic ataxia

a progressive ataxic syndrome that develops in older patients who manifest cerebellar or pontocerebellar atrophy on MRI scans, and yet who have no family history of ataxia, no identifiable gene mutations, and no known causes of acquired ataxia. Some of these patients subsequently develop signs such as parkinsonian features and autonomic failure, thereby qualifying them for the diagnosis of multiple system atrophy.
References in periodicals archive ?
Ataxia that is not related to head trauma or degenerative disease of the brain is described as sporadic idiopathic ataxia. The most common cause of this phenomenon is gluten sensitivity.
His previous research has found that gluten ataxia is the single most common cause of sporadic, idiopathic ataxia--accounting for 40% of sporadic, idiopathic ataxias and 21% of all ataxias (Brain 2003;126:685-91).
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