idiopathic aplastic anemia

idiopathic aplastic anemia

Hematology A BM stem cell defect of unknown, presumed autoimmune, etiology, in which all 3 cell–erythropoietic, myeloid and megakaryocytic–cell lines are ↓. See Aplastic anemia, Granulocytopenia, Thromboycytopenia.
References in periodicals archive ?
Bories et al., "Engraftment of allogeneic mesenchymal stem cells in the bone marrow of a patient with severe idiopathic aplastic anemia improves stroma," Leukemia, vol.
Sahu et al [1982] 53.6% of idiopathic aplastic anemia. The bone marrow biopsy in cases of aplastic anaemia reveals increased fat space, marked reduction of myeloid and erythroid cells similar to study by Saitoh et al [2002].
Hypocellular marrow was found in 13/26(50%) patients, out of them two had Fanconi anemia suggested by chromosomal breakage, two had enteric fever also suggested by positive typhi dot and nine patients had idiopathic aplastic anemia, their serology were also negative for hepatitis B and C.
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