Irrespective of the actual explanation for these differences, the presence of vCJD agent in peripheral tissues of patients during preclinical and clinical stage of the disease indicates the potential for
iatrogenic transmission of this fatal neurologic condition by surgical procedures.
1 A recent outbreak of HIV in Gujrat (National AIDS Control Programme, 2009) has further highlighted the concerns for
iatrogenic transmission of infections among the general public.
In 2011, the program underwent an International Health Regulations assessment, which concluded that the program had substantially decreased
iatrogenic transmission of HCV.
The lack of any cases, to date, of
iatrogenic transmission of pathogenic virus in recombinant therapeutics should by no means generate feelings of complacency.
Such a test might also be used to test medical instruments such as electrodes to prevent
iatrogenic transmission, as well as to detect low levels of contamination in the food supply, such as bovine spongiform encephalopathy (BSE) in cattle and scrapie in sheep, Dr.
2000), this is the largest known
iatrogenic transmission of blood-borne pathogens in the world and probably led to a massive increase in the reservoir for hepatitis C and hepatitis B (transmitted by similar means) in the general Egyptian population.
The most likely explanation is
iatrogenic transmission during his hospital admissions; however, other possibilities cannot be excluded.
In this review, the presentation, pathology and incidence of CJD are examined, with particular reference to
iatrogenic transmission.
Infection control and prevention practices need to be constantly challenged to ensure that we are truly achieving the goal of reducing the risks associated with the presence of microorganisms, particular pathogens, and preventing their
iatrogenic transmission to patients and staff.
Iatrogenic transmission of CJD has been reported from corneal transplantation, implantation of dura mater or electrodes in the brain and use of contaminated surgical instruments.
The only other examples of viruses newly transmitted between humans relate to rare instances of
iatrogenic transmission (e.
