hypromellose


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hypromellose

 [hi-pro´mә-lōs]
a propylene glycol ether of methylcellulose, supplied in differing degrees of viscosity; used as a suspending and viscosity-increasing agent and tablet binder, coating, and excipient in pharmaceutical preparations, and applied topically to the conjunctiva to protect and lubricate the cornea. Called also hydroxypropyl methylcellulose.
hypromellose phthalate a phthalic acid ester of hydroxypropyl methylcellulose, used as a coating agent for tablets and granules.

hypromellose

A preparation of METHYL CELLULOSE used as a vehicle in eye drops and as an ingredient in artificial tears.

hypromellose

A highly viscous, water-soluble, non-irritating compound used as a thickening, lubricating and clinging agent. It is used principally as artificial tears (as for example in the management of keratoconjunctivitis sicca) and sometimes as a wetting agent. Syn. hydroxypropylmethylcellulose. See alacrima; methylcellulose; 3 and 9 o'clock staining.
References in periodicals archive ?
Gelatin or a non-gelatin polymeric material such as hypromellose, water, starch, and plasticizer is used in manufacturing hard or soft gelatin capsule shells.
Tenders invited for drop,eye,hydroxypropyl methyl cellulose, hypromellose 0.3% + glycerine 0.2% + dextran 70, eye drop,hydroxy proply methycelluose & polyethylene glycol 400
At the show, the team will showcase Lonza's vegetarian Vcaps Plus capsules, made from hypromellose (HPMC) and water only.
The placebo controls contained calcium hydrogen phosphate, cellulose microcyrstalline, sodium starch glycolate, magnesium stearate, hypromellose and coating colour.
These hypromellose (HPMC) capsules are made from acid-resistant polymers to protect probiotics in the low pH stomach environment, as well as providing a modified release to allow for complete dissolution in the intestine."
For the validation of the analytical method aiming to quantify the PAR in tablet formulations a selectivity study was carried out by analyzing the UV spectra (Figure 3) obtained for PAR and the excipients (stearic acid, starch, hypromellose, macrogol and povidone).
"Patients who suffer from dry eyes have been around for a long time, but historically they would have been sent off with hypromellose eye drops," independent practice owner Mr Sohal (pictured above), told OT.
Optimization of film-coating formulation containing a novel low molecular weight hypromellose to achieve balanced tablet-coating performance--Hao Gao, Chao Wang, and Yingjie He
Antibiotic moxifloxacin (Vigamox 0.05%, Alcon) and lubricants hypromellose, (Tear Naturale II, Alcon) were advised for one week.
EyeMo comes in two variants: EyeMo Red Eyes Formula contains tetrahydrozoline HCI (for red eyes, watery eyes, sore eyes, and itchy eyes) for quick relief of eye redness and minor discomforts caused by irritants; and EyeMo Moisturizing Formula that contains hypromellose (for dry eyes) that lubricates and soothes the eyes, easing eye strain and dryness.
From literature search, six different carriers possessing P-gp inhibiting activity like Poloxamer 188, Kolliphor TPGS, Tween 80, Soluplus, Povidone (PVP K30), and Hypromellose (HPMC E5) were selected and were screened out by phase solubility study to determine the most appropriate and suitable carrier.