hypoxic stress


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hypoxic stress

). Note: the strain can be either the cause or the effect. Syn. stress. See annealing; asthenopia; hypoxia; polariscope.
References in periodicals archive ?
It is already established in previous literature that hypoxic stress resulting due to renal diseases damages regulatory mechanisms and causes further progression of kidney disease.
Mammalian cells have developed evolutionarily conserved mechanisms, including the prolyl hydroxylase domain protein(PHD-) hypoxia-inducible factors (HIFs) pathway and NF-[kappa]B, to code with hypoxic stress [73].
As expected, hypoxia exposure to HSCs alone led to significant PPAR[gamma] downregulation and [alpha]-SMA and desmin rise, whereas cotreatment with hypoxia and RSG reversed these effects (Figure 2(b)), indicating that PPAR[gamma] antagonizes HSCs activation caused by hypoxic stress.
The different conditions through which animals are exposed to hypoxic stress appear to differentially activate cellular responses discussed herein.
On long-term hypoxic stress, there is an energy deprivation in tumor cell which results in elevated AMP/ATP ratio, leading to the activation of AMPK, a major regulator of cellular energy homeostasis.
The circulating levels of BDNF in humans have been shown to increase dramatically during hypoxic stress, both in the perinatal period [109] and adulthood [110, 111] which, in turn, inhibits the ER stress activation as well as ROS production [112].
Recently, the impact of hypoxic stress in HLA-G expression in U251MG glioblastoma cell line was explored [32].
Hypoxic stress was induced for 24 h in a hypoxic chamber (Stem Cell Technology, USA), with the [O.sub.2] concentration controlled by an [O.sub.2] sensor and maintained at 0.1%.
In Experiment 1, in fact, final mean juvenile dry weights after embryos had been exposed to hypoxia for 24 h or 36 h were significantly higher (24 h: t-test = 2.33, P = 0.023; 36 h: t-test = 3.44, P = 0.001; mixed model analysis) than what was recorded for control individuals that had experienced no hypoxic stress (Fig.
The key may be in a small protein called hypoxia-inducible factor-2 alpha (HIF2a), one of a family of transcription factors that enable cells to respond to hypoxic stress.
The key may be in a small protein called hypoxia-inducible factor-2 alpha (HIF-2a), one of a family of transcription factors that enable cells to respond to hypoxic stress.
Stereological evaluation of vascular adaptations in human placental villi to differing forms of hypoxic stress. Placenta.