hypoxia-inducible factor


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hypoxia-inducible factor

A factor within aerobic cells that helps them adapt to abnormally low oxygen concentrations.
See also: factor
References in periodicals archive ?
Downregulation and pro-apoptotic effect of hypoxia-inducible factor 2 alpha in hepatocellular carcinoma.
Hypoxia-inducible factor 1a-induced epithelial-mesenchymal transition of endometrial epithelial cells may contribute to the development of endometriosis.
Regulation of cancer cell metabolism by hypoxia-inducible factor 1.
EBV latent membrane protein 1 up-regulates hypoxia-inducible factor 1[alpha] through Siah1-mediated down-regulation of prolyl hydroxylases 1 and 3 in nasopharyngeal epithelial cells," Cancer Research, vol.
Differentiated embryonic chondrocyte-expressed gene 1 is associated with hypoxia-inducible factor 1a and Ki67 in human gastric cancer," Diagnostic Pathology, vol.
digitifera hypoxia-inducible factor la gene (HIF1A), and two were found to be significant in the transcriptome-wide ANOVA (FDR corrected P < 0.
Insulin-like growth factor 1 induces hypoxia-inducible factor 1-mediated vascular endothelial growth factor expression, which is dependent on MAP kinase and phosphatidylinositol 3-kinase signaling in colon cancer cells.
Semenza's research group studies a chemical signal alled hypoxia-inducible factor 1 (HIF-
Dimerization, DNA binding, and transactivation properties of hypoxia-inducible factor 1.
Much evidence has indicated that hypoxia (both chronic and acute/cyclic) affects various aspects of tumorigenesis frequently through induction of the hypoxia-inducible factor (HIF) transcription factors [26].
In part with the hypoxia-inducible factor (HIF) signaling pathway, COC extract administration significantly upregulated the prolyl hydroxylase-2 level.

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