xanthine oxidase
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xan·thine ox·i·dase
a flavoprotein containing molybdenum; an oxidoreductase catalyzing the reaction of xanthine, O2, and H2O to produce urate and superoxide. Also oxidizes hypoxanthine, some other purines and pterins, and aldehydes. A lower rate of oxidation is observed in patients with molybdenum cofactor deficiency.
Synonym(s): hypoxanthine oxidase, Schardinger enzyme
xanthine oxidase
/xan·thine ox·i·dase/ (ok´sĭ-dās) a flavoprotein enzyme that catalyzes the oxidation of hypoxanthine to xanthine and then to uric acid, the final steps in the degradation of purines; deficiency, an autosomal recessive trait, causes xanthinuria.xan·thine ox·i·dase
(zanthēn oksi-dās)Flavoprotein containing molybdenum; also oxidizes hypoxanthine, some other purines and pterins, and aldehydes.
Schardinger,
Franz, Austrian scientist, 1853-1920.Schardinger dextrins - the result of action of Bacillus macerans on starch.
Schardinger enzyme - a flavoprotein containing molybdenum. Synonym(s): xanthine oxidase
Schardinger reaction - an example of oxidation in the absence of O2 with an organic hydrogen acceptor.
xanthine
a purine compound found in most bodily tissues and fluids; it is a precursor of uric acid. Xanthine compounds such as theophylline have diuretic properties.
xanthine calculi
see xanthine urolith.
dimethyl xanthine
theobromine.
xanthine oxidase
key enzyme in the pathway for purine breakdown. Catalyzes the conversion of hypoxanthine to xanthine and then to uric acid. Generates hydrogen peroxide, which can be a generator of free radicals in biological systems through reactions with superoxide ions.
trimethyl xanthine
caffeine.