hypoxanthine


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hypoxanthine

 [hi″po-zan´thēn]
an intermediate product of uric acid synthesis, formed from adenylic acid and itself a precursor of xanthine.

hy·po·xan·thine (Hyp),

(hī'pō-zan'thin),
6-Oxypurine; purin-6(1H)-one; a purine present in the muscles and other tissues, formed during purine catabolism by deamination of adenine; elevated in molybdenum-cofactor deficiency.
Synonym(s): 6-hydroxypurine

hypoxanthine

/hy·po·xan·thine/ (-zan´thēn) a purine base formed as an intermediate in the degradation of purines and purine nucleosides to uric acid and in the salvage of free purines. Complexed with ribose it is inosine.

hy·po·xan·thine

(hī'pō-zan'thēn)
A purine present in the muscles and other tissues, formed during purine catabolism by deamination of adenine; elevated in molybdenum-cofactor deficiency.

hy·po·xan·thine

(hī'pō-zan'thēn)
A purine present in the muscles and other tissues.

hypoxanthine (hī´pōzan´thēn),

n a purine present in the muscles and other tissues, formed during purine catabolism by deamination of adenine.

hypoxanthine

an intermediate product of uric acid synthesis, formed from adenylic acid and itself a precursor of xanthine.
References in periodicals archive ?
The increase in XO activity observed in cholelithiasis patients reflect the fact that the catabolic pathway of hypoxanthine and xanthine is increased, this increase may confirmed by increasing in uric acid levels.
The increase in XOR activity detected in atherosclerosis patients reflects the detail that the catabolic pathway is increased in a way to produce hypoxanthine and xanthine in order to permit its readiness to recycle to IMP.
The "Low RR" solutes' group (RR [less than or equal to] 50%) included the protein bound solute indoxyl sulphate and the small water soluble compound hypoxanthine.
In previous studies, xanthine oxidase, the enzyme that converts hypoxanthine to uric acid, was inhibited in vitro by polyphenols.
Plasma accumulation of hypoxanthine, uric acid and creatine kinase following exhausting runs of differing durations in man.
Recently, the active principle that initiates microstomal to macrostomal differentiation has been identified as an ferrous iron chelate of hypoxanthine (6 hydroxy-purine) and uracil (2,4-dioxyprymidine) (Smith-Somerville et al.
Methods: Spleen cells of female BALB/c mice immunized with O group red cells were fused in presence of polyethylene glycol (PEG) 1500 with a mouse myeloma cell line Sp2/0 Ag14 in hypoxanthine aminopterine thymidine (HAT) selective medium and incubated at 37[degrees]C, 5 per cent C[O.
The resulting cells were distributed into micro-well plates in hypoxanthine aminopterin thymidine medium which killed off the fusion partners, in that each well was left with one hybridoma cell.
Vitreous humor hypoxanthine levels in SIDS and infectious death.
Allopurinol inhibits xanthine oxidase, which is needed to convert hypoxanthine to xanthine to uric acid, thereby decreasing the production and lowering blood levels of uric acid.
Researcher Professor Nick Dale has been examining a chemical found in the blood - hypoxanthine - used to discover whether a child may be starved of oxygen.
27,28) Likewise, in two small prospective studies (n = 7 and 8, respectively) involving coronary artery bypass graft patients without religious objections to transfusion, normovolemic hemodilution to a hematocrit of l5% was well tolerated during surgery, (29) without evidence of myocardial ischemia on electrocardiogram and without affecting either lactate extraction or hypoxanthine release.