hypoxanthine


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Related to hypoxanthine: inosine, Hypoxanthine phosphoribosyltransferase, hypoxanthine oxidase

hypoxanthine

 [hi″po-zan´thēn]
an intermediate product of uric acid synthesis, formed from adenylic acid and itself a precursor of xanthine.

hy·po·xan·thine (Hyp),

(hī'pō-zan'thin),
6-Oxypurine; purin-6(1H)-one; a purine present in the muscles and other tissues, formed during purine catabolism by deamination of adenine; elevated in molybdenum-cofactor deficiency.
Synonym(s): 6-hydroxypurine

hypoxanthine

/hy·po·xan·thine/ (-zan´thēn) a purine base formed as an intermediate in the degradation of purines and purine nucleosides to uric acid and in the salvage of free purines. Complexed with ribose it is inosine.

hy·po·xan·thine

(hī'pō-zan'thēn)
A purine present in the muscles and other tissues, formed during purine catabolism by deamination of adenine; elevated in molybdenum-cofactor deficiency.

hy·po·xan·thine

(hī'pō-zan'thēn)
A purine present in the muscles and other tissues.

hypoxanthine (hī´pōzan´thēn),

n a purine present in the muscles and other tissues, formed during purine catabolism by deamination of adenine.

hypoxanthine

an intermediate product of uric acid synthesis, formed from adenylic acid and itself a precursor of xanthine.
References in periodicals archive ?
Both HA, being a protein-bound solute, but also the small non-proteinbound compound hypoxanthine, have individual removal patterns, which should be considered when analysing the removal of uremic solutes during hemodialysis.
This model is consistent with coordination potential between hypoxanthine and uracil, however, several other structures are possible.
8] Human genes: HPRT1, hypoxanthine phosphoribosyltransferase 1; HPRT1, hypoxanthine phosphori bosyltransferase 1; RPLPO, ribosomal protein, large, PO; ERBB2, v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2; AR, androgen receptor; ERBB4, v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4.
In buffalo and cattle, the xanthine oxidase (XO) activity in intestinal mucosa and liver is too high to permit any uptake of salvageable PD, xanthine and hypoxanthine [17].
The selected mutant strains with nrt (nitrate transporter) phenotypes have shown wild-type growth on (10 mM) nitrate, nitrite and hypoxanthine, in addition of being highly resistant to (200 mM) chlorate (The toxic analogue of nitrate) and / or bromate (The toxic analogue of nitrite) (Fig 1 c,d).
Chromium (III) tris (picolinate) is mutagenic at the hypoxanthine (guanine) phosphoribosyltransferase locus in Chinese hamster ovary cells.
9:20 QUANTUM CHEMICAL INVESTIGATIONS OF EXCITED STATE PROPERTIES OF HYPOXANTHINE
Irvine, CA; 949-788-6700) announced that the company has been issued United States Patent 6,303,617 entitled "Novel Serotonin-Like 9-Substituted Hypoxanthine and Methods of Use.
The scientists engineered a strain of mice that has 146 extra CAG repeats in a gene that encodes hypoxanthine phosphoribosyltransferase (HPRT), an enzyme used by all cells.
It acts upstream of xanthine and hypoxanthine in the purine metabolic pathway to reduce serum uric acid (sUA) in patients with gout and has a mechanism of action that complements xanthine oxidase inhibitors, such as allopurinol and febuxostat, in reducing uric acid production.
The kit utilizes a tetrazolium salt for detection of superoxide radicals generated by xanthine oxidase and hypoxanthine.