Hypouricemia, abnormal renal tubular urate transport, and plasma natriuretic factor(s) in patients with Alzheimer's disease.
The control was her father, who was in good health and for whom renal dysfunction,
hypouricemia, albuminuria, and hematuria were excluded; his blood sample was obtained as described above.
Romitelli et al., "
Hypouricemia linked to an overproduction of nitric oxide is an early marker of oxidative stress in female subjects with type 1 diabetes," Diabetes/Metabolism Research and Reviews, vol.
Fanconi Syndrome, characterized by normoglycemic glycosuria, hypophosphatemia, aminoaciduria, proteinuria, metabolic acidosis, and
hypouricemia, may be caused by NtRTIs (like TDF) [16] and is widely reported in HIV-infected patients, also pediatric.
Various mutations of SLC2A9 were found in
hypouricemia patients: Ile118HisfsX27 in a Czech family [23], exon 7 deletion in Ashkenazi Jewish [24], and R380W and R198C in Japanese [25].
Kuwabara et al., "Depletion of uric acid due to SLC22A12 (URAT1) loss-of-function mutation causes endothelial dysfunction in
hypouricemia," Circulation Journal, vol.
(6) Signs of proximal renal tubular dysfunction include proteinuria, glucosuria, hypophosphatemia,
hypouricemia, hypokalemia, low serum bicarbonate and/or elevated serum creatinine.
Serum biochemical analysis revealed hypoproteinemia (2.7 g/dL [27 g/L]; reference interval, 2.9-4.14 g/dL [29.0-41.4 g/L]), hypoalbuminemia (0.8 g/dL [8 g/ L]; reference interval, 1.11-1.35 g/dL [11.1-13.5 g/ L]), hypoglobulinemia (1.9 g/dL [19 g/L]; reference interval, 2.35-2.84 g/dL [23.5-28.4 g/L]),
hypouricemia (3.13 mg/dL [186 [micro]mol/L]; reference interval, 6.94-9.68 mg/dL [413-576 [micro]mol/L]), low bile acids (0.82 [micro]g/mL [2 pmol/L]; reference interval, 8.17-36.76 [micro]g/mL [20-90 [micro]mol/L]), hyperglycemia (419 mg/dL [23.3 mmol/L]; reference interval, 183.8-261.3 mg/dL [10.2-14.5 mmol/L]), and hypocalcemia (8 mg/dL [2 mmol/L]; reference interval, 8.8-10.64 mg/dL [2.21-2.66 mmol/L]).
Tsuji, "The xanthine oxidase inhibitory activity and
hypouricemia effect of the propolis in rats," Yakugaku Zasshi, vol.
Individuals with congenital URAT1 deficiencies demonstrate
hypouricemia, hyperuricosuria, and in some cases exercise-induced renal failure.
Hypouricemia and hyperuricemia in type 2 diabetes: two different phenotypes.